DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PEX3 and Pex3

DIOPT Version :10

Sequence 1:NP_003621.1 Gene:PEX3 / 8504 HGNCID:8858 Length:373 Species:Homo sapiens
Sequence 2:NP_112640.1 Gene:Pex3 / 83519 RGDID:621636 Length:372 Species:Rattus norvegicus


Alignment Length:373 Identity:351/373 - (94%)
Similarity:361/373 - (96%) Gaps:1/373 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MLRSVWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTC 65
            ||||:|||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||
  Rat     1 MLRSMWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKLREIQEREAAEYIAQARRQYHFESNQRTC 65

Human    66 NMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLR 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||
  Rat    66 NMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSIVAVYSTCMLVVLLR 130

Human   131 VQLNIIGGYIYLDNAAVGKNGTTILAPPDVQQQYLSSIQHLLGDGLTELITVIKQAVQKVLGSVS 195
            |||||||||||||||.||||||:||||||||||||||||||||||||||:||||||||::|||:|
  Rat   131 VQLNIIGGYIYLDNATVGKNGTSILAPPDVQQQYLSSIQHLLGDGLTELVTVIKQAVQRILGSIS 195

Human   196 LKHSLSLLDLEQKLKEIRNLVEQHKSSSWINKDGSKPLLCHYMMPDEETPLAVQACGLSPRDITT 260
            ||||||||||||||||||.|||||: |.|.:||.||..||||||||||||||.||.|||||||||
  Rat   196 LKHSLSLLDLEQKLKEIRTLVEQHR-SCWNDKDASKSSLCHYMMPDEETPLAAQAYGLSPRDITT 259

Human   261 IKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKI 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||
  Rat   260 IKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSINSLSSVSLPLAKI 324

Human   326 IPIVNGQIHSVCSETPSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK 373
            ||||||||||||||||||||||||.|||||||||||||||||||||||
  Rat   325 IPIVNGQIHSVCSETPSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PEX3NP_003621.1 Targeting to peroxisomes. /evidence=ECO:0000269|PubMed:11390669 1..45 41/43 (95%)
Peroxin-3 11..362 CDD:428171 329/350 (94%)
Interaction with PEX19. /evidence=ECO:0000269|PubMed:11390669 120..136 15/15 (100%)
Pex3NP_112640.1 Targeting to peroxisomes. /evidence=ECO:0000250|UniProtKB:P56589 1..45 41/43 (95%)
Peroxin-3 11..361 CDD:428171 329/350 (94%)
Interaction with PEX19. /evidence=ECO:0000250|UniProtKB:P56589 120..136 15/15 (100%)

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