Protein Alignment PEX3 and pex3

DIOPT Version :10

• Sequence 1: NP_003621.1
• Gene: PEX3 / 8504
• HGNCID: 8858
• Length: 373
• Species: Homo sapiens
• Sequence 2: NP_001039031.1
• Gene: pex3 / 733783
• XenbaseID: XB-GENE-954958
• Length: 369
• Species: Xenopus tropicalis
• Alignment Length: 370
• Identity: 289/370 - (78%)
• Similarity: 326/370 - (88%)
• Gaps: 3/370 - (0%)

Human     4 SVWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMT 68
            |:||||||||||.||:|.|.||||:||||.|:|||||||||||||||||||||||||||||||||
 Frog     3 SMWNFLKRHKKKFIFVGAVAGGVYLLGKYAQRKIREIQEREAAEYIAQARRQYHFESNQRTCNMT 67

Human    69 VLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLRVQL 133
            ||||||.|||.|||||||||||:||||:||||||||||||||||:||.|||||||||||||||||
 Frog    68 VLSMLPALREGLMQQLNSESLTSLLKNKPSNKLEIWEDLKIISFSRSIVAVYSTCMLVVLLRVQL 132

Human   134 NIIGGYIYLDNAAVGKNGTTILAPPDVQQQYLSSIQHLLGDGLTELITVIKQAVQKVLGSVSLKH 198
            |||||||||||:::.|||||:.|.|:|||||||||||||||||:|||||:|||||.||||.||||
 Frog   133 NIIGGYIYLDNSSLTKNGTTLQASPEVQQQYLSSIQHLLGDGLSELITVVKQAVQGVLGSFSLKH 197

Human   199 SLSLLDLEQKLKEIRNLVEQHKSSSWINKDGSKPLLCHYMMPDEETPLAVQACGLSPRDITTIKL 263
            ..||.:||||:||||:|||:.|.|....:..||..||.|:|||||.||..||.||:.:|:.||:|
 Frog   198 CFSLTELEQKIKEIRSLVEKKKGSLNGEESDSKSKLCQYLMPDEENPLTTQAYGLTEKDVLTIRL 262

Human   264 LNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKIIPI 328
            ||||||||||.||.||||:||:|||.||||:.|||||||::::   |..|:|.|:||||||||||
 Frog   263 LNETRDMLESEDFKTVLNSCLSRGFGRLLDSTAEFFRPTDREM---NQDNTLHSISLPLAKIIPI 324

Human   329 VNGQIHSVCSETPSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK 373
            :||||||:|||.|:|||||||.|||||:|||||||||||||||||
 Frog   325 INGQIHSICSEMPNHFVQDLLLMEQVKNFAANVYEAFSTPQQLEK 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX3	NP_003621.1	Targeting to peroxisomes. /evidence=ECO:0000269|PubMed:11390669	1..45		32/40 (80%)
		Peroxin-3	11..362	CDD:428171	270/350 (77%)
		Interaction with PEX19. /evidence=ECO:0000269|PubMed:11390669	120..136		15/15 (100%)
pex3	NP_001039031.1	Peroxin-3	10..358	CDD:428171	270/350 (77%)