Protein Alignment PEX3 and pex3

DIOPT Version :10

• Sequence 1: NP_003621.1
• Gene: PEX3 / 8504
• HGNCID: 8858
• Length: 373
• Species: Homo sapiens
• Sequence 2: NP_956522.1
• Gene: pex3 / 393197
• ZFINID: ZDB-GENE-040426-979
• Length: 364
• Species: Danio rerio
• Alignment Length: 377
• Identity: 278/377 - (73%)
• Similarity: 317/377 - (84%)
• Gaps: 17/377 - (4%)

Human     1 MLRSVWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTC 65
            ||.|.|||:||||:|.||.|..:||||:||||.|:||:|:|||||||||||||||:|||||||||
Zfish     1 MLSSTWNFIKRHKRKFIFTGVFVGGVYLLGKYAQRKIQEMQEREAAEYIAQARRQFHFESNQRTC 65

Human    66 NMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLR 130
            ||||||||||||||::..|||||||.|||.:|:|||||||||||||||||.||||||||||||||
Zfish    66 NMTVLSMLPTLREAIIHHLNSESLTTLLKTKPANKLEIWEDLKIISFTRSIVAVYSTCMLVVLLR 130

Human   131 VQLNIIGGYIYLDNAAVGKNGTTILAPPDVQQQYLSSIQHLLGDGLTELITVIKQAVQKVLGSVS 195
            |||||||||:|||| :|.|||.|.|||||||||||||||||||:||.|||||:|:|||:|.|.||
Zfish   131 VQLNIIGGYLYLDN-SVTKNGMTPLAPPDVQQQYLSSIQHLLGEGLMELITVVKKAVQEVFGLVS 194

Human   196 LKHSLSLLDLEQKLKEIRNLVE----QHKSSSWINKDGSKPLLCHYMMPDEETPLAVQACGLSPR 256
            ||.||||.:|||:|.:||.|||    ::|..||            |||||||..||.|||||:..
Zfish   195 LKQSLSLQELEQQLTQIRQLVEDDSSKYKGLSW------------YMMPDEENTLASQACGLTEN 247

Human   257 DITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLP 321
            |:||||||||||||||||||:.||:|||||||.|.||||||||||.::|....::.:.||.||||
Zfish   248 DVTTIKLLNETRDMLESPDFNIVLHTCLNRGFVRFLDNMAEFFRPPQRDSTPSSTPDQLSHVSLP 312

Human   322 LAKIIPIVNGQIHSVCSETPSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK 373
            |||||||:||||||:|||.|||||||||.::|||:|||||||.|||||:|:|
Zfish   313 LAKIIPIINGQIHSICSEIPSHFVQDLLLIDQVKEFAANVYETFSTPQELQK 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX3	NP_003621.1	Targeting to peroxisomes. /evidence=ECO:0000269|PubMed:11390669	1..45		29/43 (67%)
		Peroxin-3	11..362	CDD:428171	261/354 (74%)
		Interaction with PEX19. /evidence=ECO:0000269|PubMed:11390669	120..136		15/15 (100%)
pex3	NP_956522.1	Peroxin-3	11..353	CDD:428171	261/354 (74%)