Protein Alignment RBM17 and Spf45

DIOPT Version :10

• Sequence 1: NP_116294.1
• Gene: RBM17 / 84991
• HGNCID: 16944
• Length: 401
• Species: Homo sapiens
• Sequence 2: NP_001036426.1
• Gene: Spf45 / 3355114
• FlyBaseID: FBgn0086683
• Length: 403
• Species: Drosophila melanogaster
• Alignment Length: 456
• Identity: 161/456 - (35%)
• Similarity: 219/456 - (48%)
• Gaps: 113/456 - (24%)

Human     1 MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSDD 65
            |.|||.:......|:.:|||...|:||:||.||.|.          :..::.||::|:....:|.
  Fly     1 MDLYDGIDTRARSSQIDGWSSGIKMLQTQLAVKMAV----------KKPLMTPVVNLRSKRLADP 55

Human    66 RQIVDTPPHVAAGLKDPVPSGFSAGEVL-------IPLADEYDPMFPNDYEKVVKRQREERQRQR 123
            ......|  :...:..|:.||.:...:|       ..:||||||..||:|||:.::.....:.:.
  Fly    56 EVTCFAP--ITTVVSKPLISGKALPSILERINRGDWDVADEYDPQRPNEYEKLKEKSNGSDKNRA 118

Human   124 ELERQKEIEEREKRRK----DRHE------------ASGFARRPDPDSDEDEDYERERRKRSMGG 172
            .:..:::.:::||.||    .|.|            .|||..|   .:|:|............||
  Fly   119 GVSDREDRDDKEKDRKRGRVGRREFYRDEVSAPNLKLSGFGHR---QNDDDMYLPSPGLVAKQGG 180

Human   173 AAIAPPTSL----VEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLAN 233
            |.||||.||    ::...|.....||...|
  Fly   181 ATIAPPPSLQEMSIDSGCEATNTMPYSASS----------------------------------- 210

Human   234 MGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKII----------------VGDA 282
                ||.|||.||||::||||||.|||::.||.|||||||||:||                :|..
  Fly   211 ----VAAKIMAKYGFKDGQGLGKSEQGMAIALQVEKTSKRGGRIIHEKDVFLPPLALSPPSIGSQ 271

Human   283 TEKDASKKSDSNP---------------LTEILKCPTKVVLLRNMVGAGEVDEDLEVETKEECE- 331
            .....|.|:...|               :|||:|.|:||||||||||.|:|||:||.|.|:||.
  Fly   272 IGTSPSHKAMPPPQMVDTAAESGDIGYSITEIMKSPSKVVLLRNMVGPGDVDEELEPEVKDECNT 336

Human   332 KYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLD 396
            |||:|...:|.|..|...::||:||:||.|:|||||||||||||:||||.|:|.|||.|||:...
  Fly   337 KYGEVNSVIIHESFGTVPEDAVKIFVEFRRIESAIKAVVDLNGRFFGGRQVRAGFYNYDKFKCFQ 401

Human   397 L 397
            |
  Fly   402 L 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM17	NP_116294.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	57..84		4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..233		25/138 (18%)
		G-patch	235..279	CDD:396249	31/59 (53%)
		RRM_UHM_SPF45	303..397	CDD:410051	60/94 (64%)
Spf45	NP_001036426.1	G-patch	209..248	CDD:396249	28/77 (36%)
		RRM_UHM_SPF45	307..402	CDD:410051	60/94 (64%)