Protein Alignment IGSF21 and Igsf21

DIOPT Version :9

• Sequence 1: NP_116269.3
• Gene: IGSF21 / 84966
• HGNCID: 28246
• Length: 467
• Species: Homo sapiens
• Sequence 2: NP_001258383.1
• Gene: Igsf21 / 298591
• RGDID: 1310117
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 468
• Identity: 443/468 - (94%)
• Similarity: 451/468 - (96%)
• Gaps: 1/468 - (0%)

Human     1 MRTAPSLRRCVCLLLAAILDLARGYLTVNIEPLPPVVAGDAVTLKCNFKTDGRMREIVWYRVTDG 65
            ||.||||||..||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MRAAPSLRRASCLLLAAILDLARGYLTVNIEPLPPVVAGDAVTLKCNFKTDGRMREIVWYRVTDG 65

Human    66 GTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGIYDRATREKVV 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 GTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGIYDRATREKVV 130

Human   131 LASGNIFLNVMAPPTSIEVVAADTPAPFSRYQAQNFTLVCIVSGGKPAPMVYFKRDGEPIDAVPL 195
            |||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||
  Rat   131 LASGNIFLNVMAPPTSIEVVAADSPAPFSRYQAQNFTLVCIVSGGKPAPMVYFKRDGEPIDAVPL 195

Human   196 SEPPAASSGPLQDSRPFRSLLHRDLDDTKMQKSLSLLDAENRGGRPYTERPSRGLTPDPNILLQP 260
            :|.||:|||.:|||||||||||||:|||||||||||||.|.|.||||||||||.||.|||:.:||
  Rat   196 TELPASSSGSVQDSRPFRSLLHRDVDDTKMQKSLSLLDTEYRAGRPYTERPSRSLTQDPNLFVQP 260

Human   261 TTENIPETVVSREFPRWVHSAEPTYFLRHSRTPSSDGTVEVRALLTWTLNPQIDNEALFSCEVKH 325
            |||||||||||||||||||||||.|||||||||.|||||||||||||||||||||||||||||||
  Rat   261 TTENIPETVVSREFPRWVHSAEPVYFLRHSRTPGSDGTVEVRALLTWTLNPQIDNEALFSCEVKH 325

Human   326 PALSMPMQAEVTLVAPKGPKIVMTPSRARVGDTVRILVHGFQNEVFPEPMFTWTRVGSRLLDGSA 390
            |||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
  Rat   326 PALSMPMQAEVTLVAPKGPKIMMTPSRARVGDTVRILVHGFQNEVFPEPMFTWTRVGSRLLDGSA 390

Human   391 EFDGKELVLERVPAELNGSMYRCTAQNPLGSTDTHTRLIVFENPNIPRGTEDSNGSI-GPTGARL 454
            |||||||||||||||||||||||||||||||||||||||||||||||||||||.||. ||||.||
  Rat   391 EFDGKELVLERVPAELNGSMYRCTAQNPLGSTDTHTRLIVFENPNIPRGTEDSRGSASGPTGVRL 455

Human   455 TLVLALTVILELT 467
            |||||||||||||
  Rat   456 TLVLALTVILELT 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IGSF21	NP_116269.3	IG_like	36..140	CDD:214653	103/103 (100%)
		Ig	39..130	CDD:299845	90/90 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..259		22/29 (76%)
		IG_like	353..430	CDD:214653	76/76 (100%)
		Ig	369..432	CDD:299845	62/62 (100%)
Igsf21	NP_001258383.1	Ig	39..130	CDD:325142	90/90 (100%)
		Ig	372..432	CDD:325142	59/59 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83684490
Domainoid	1	1.000	650	1.000	Domainoid score	I4146
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13153
Inparanoid	1	1.050	891	1.000	Inparanoid score	I6522
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG45061
OrthoDB	1	1.010	-	-		D124878at32523
OrthoFinder	1	1.000	-	-		FOG0010639
OrthoInspector	1	1.000	-	-		oto141022
orthoMCL	1	0.900	-	-		OOG6_115231
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X8133
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	15.310