Protein Alignment CGNL1 and Prm

DIOPT Version :9

• Sequence 1: XP_005254783.1
• Gene: CGNL1 / 84952
• HGNCID: 25931
• Length: 1303
• Species: Homo sapiens
• Sequence 2: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 885
• Identity: 207/885 - (23%)
• Similarity: 379/885 - (42%)
• Gaps: 187/885 - (21%)

Human   509 RATATSPDSGAKKISVKTFPSASNTQATPDL-------LKGQQELTQQTNEETAK---QILYNYL 563
            |||:|.|  |...::::.....|:.....|.       |:.::||.|:...|.|.   |::....
  Fly    15 RATSTGP--GTADVNIEYIQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSE 77

Human   564 K----EGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVA 624
            :    ||..::.....||.:....|::.|.           :..:..||...||.:|....| :.
  Fly    78 RLEEAEGGAEHQFEANRKRDAELLKLRKLL-----------EDVHLESEETTLLLKKKHNEI-IT 130

Human   625 ELQRQLQLEVKNQQNIKEERERMRANLEELRSQ----HNEKVEENSTLQQRLEESEGELRKNLEE 685
            :.|.|:::..||:...::::.:.:..:.||.||    :.||:.....: .:||.|..||...:||
  Fly   131 DFQEQVEILTKNKARAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHI-SKLEVSISELNVKIEE 194

Human   686 LFQVKMEREQHQT-----------EIRDLQDQL-------SEMHDELDSAKR---SEDREKGALI 729
            |.:..::...|::           :::||:.||       |::..:|:.|:|   .|||.:..|.
  Fly   195 LNRTVIDISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLE 259

Human   730 EELLQAKQDLQDLLIAKEEQEDLLRKREREL-------TALKGALKEEVSSHDQEMDKLKEQYDA 787
            ..|.|.:.:|..:....||:.:.....||:|       |:.:.....||::..:|:::::.:|..
  Fly   260 SSLHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQV 324

Human   788 ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQI 852
            .:..|.|       ::|.|..:.|..|:.:......|::|..:.||......||.:.|..|::..
  Fly   325 RITELEE-------HIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHN 382

Human   853 EDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQ 917
            .:||   ::..||:..||...|.|         :.|.|...|..  :||:..:.|.:|.|:|.|:
  Fly   383 VELK---SRLDETIILYETSQRDL---------KNKHADLVRTV--HELDKVKDNNNQLTRENKK 433

Human   918 LSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADI------VEASRTSTLE----LQ 972
            |.:.|.|......:|.|..:|:|.|       :.:|:.|..::      .||.|.:..:    |.
  Fly   434 LGDDLHEAKGAINELNRRLHELELE-------LRRLENERDELTAAYKEAEAGRKAEEQRGQRLA 491

Human   973 NQLDEYKEKNRRELAEMQ--------------RQLKEKTLEAE---KSRLTAMKMQDEMRLMEEE 1020
            ...::|:....|.|||..              .||..:.:|||   |:.:|.:|.:.::::.|.|
  Fly   492 ADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITELE 556

Human  1021 L------------------------------RDYQRAQDEALTKRQLLEQTLKDLEYEL-EAKSH 1054
            :                              .|.||.....|.:..:.::.|..|..|| |.:||
  Fly   557 MSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSH 621

Human  1055 LKDDRSRLVKQMEDKV---------------------SQLEMELEEERNNSDLLSE--RISRSRE 1096
            | |..:|..:.:|.:.                     |:||.||....::.:.:|:  |||..|.
  Fly   622 L-DSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERY 685

Human  1097 Q---------MEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQME 1152
            |         :||:..|  |||..:  ||..|.|||.:.|:|..|:..:|.:..:..:.::.::|
  Fly   686 QKVQVELKHVVEQVHEE--QERIVK--LETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKLE 746

Human  1153 ARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLSLRLKAMKRQ 1214
            |||.:||..||.|:|..|......|:.||.|||:::|.:::.   :.|.|..|:.:.::...:||
  Fly   747 ARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQ 811

Human  1215 VEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 1254
            :.|.|....:..:..::.|||||...|..:..:..||.::
  Fly   812 LSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIR 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CGNL1	XP_005254783.1	Taxilin	608..943	CDD:286771	88/366 (24%)
		SPEC	694..>856	CDD:295325	40/189 (21%)
		DUF4200	839..924	CDD:290574	24/84 (29%)
		Tropomyosin	843..1089	CDD:278679	69/324 (21%)
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	201/864 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910