Protein Alignment RAB2B and VPS21

DIOPT Version :9

• Sequence 1: NP_116235.2
• Gene: RAB2B / 84932
• HGNCID: 20246
• Length: 216
• Species: Homo sapiens
• Sequence 2: NP_014732.1
• Gene: VPS21 / 854256
• SGDID: S000005615
• Length: 210
• Species: Saccharomyces cerevisiae
• Alignment Length: 216
• Identity: 77/216 - (35%)
• Similarity: 120/216 - (55%)
• Gaps: 24/216 - (11%)

Human     8 KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSIT 72
            |.:::|:..||||.::|:|....|....:.|||..|..:.|.|:...:|.:||||||||.|.|:.
Yeast     9 KLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLA 73

Human    73 RSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDL---ESRRDVKREEG 134
            ..|||.|..||:|||:|:.::|.....|:::..:.:|.:::|.|:|||.|:   ...|.|.||||
Yeast    74 PMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVAREEG 138

Human   135 EAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGP 199
            |..|.|.||:|.||||||..||.:.|:...::|                .:|...:|:.:::...
Yeast   139 EKLAEEKGLLFFETSAKTGENVNDVFLGIGEKI----------------PLKTAEEQNSASNERE 187

Human   200 SASQR---NSRDIG--SNSGC 215
            |.:||   |:.:.|  :||.|
Yeast   188 SNNQRVDLNAANDGTSANSAC 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB2B	NP_116235.2	PLN03108	1..216	CDD:178655	77/216 (36%)
		Effector region. /evidence=ECO:0000250	35..43		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..216		9/32 (28%)
VPS21	NP_014732.1	Rab5_related	7..172	CDD:206653	67/178 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910