Protein Alignment ALG10 and Alg10

DIOPT Version :9

• Sequence 1: NP_116223.3
• Gene: ALG10 / 84920
• HGNCID: 23162
• Length: 473
• Species: Homo sapiens
• Sequence 2: NP_729680.1
• Gene: Alg10 / 326193
• FlyBaseID: FBgn0052076
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 456
• Identity: 149/456 - (32%)
• Similarity: 228/456 - (50%)
• Gaps: 56/456 - (12%)

Human    36 MDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSIGVIKPAIWIFGWSEHVVCSIGMLRFVN 100
            :||.||:||...:|...|.:  |||.|||.|||||::: ::.|.         .:|::..||.::
  Fly    32 IDEEFHIPQGLAFCRKEFDV--WDPKITTFPGLYLIAL-LLNPL---------SLCTVTGLRMLS 84

Human   101 LLFSVGNFYLLYLLFCKVQPRNKAAS--SIQRVLSTLTLAVFPTLYFFNFLYYTEAGSMFFTLFA 163
            |..:..|..|||    |::.|..|.|  :.......:|::|.|.||||:.||||:..|:...|..
  Fly    85 LAGAGINILLLY----KIRRRILAGSGGNSYAAHEAITMSVLPPLYFFSHLYYTDTLSLTMVLLF 145

Human   164 YLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAW---------KTELQKKEDR 219
            |.......|..:|..|....:.|||||:|.....|..:...|....         ...|..||..
  Fly   146 YNYWQQEAHLPAAVFGAASVLMRQTNIVWVCMATGMTVLDTLVNQCARTGRVPKENVRLMGKELW 210

Human   220 LPPIKGPFAEFRKILQFLLAYSMSFKNLSMLLLLTWPYILLGFLFCAFVVVNGGIVIGDRSSHEA 284
            |..:..|......||. :||....:.::.:      |::  ||||     :||.||:||:|:|||
  Fly   211 LQLVSSPQLLCNCILS-ILAKCCFYASIIL------PFV--GFLF-----INGSIVVGDKSAHEA 261

Human   285 CLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKRRILFFVVTLVSVFLVWKFTYAHKYLLA 349
            .||.||||||..|...|...:.:  .:.:....|:.:.|:|..:..|:.:.:|...|..|.||||
  Fly   262 SLHVPQLFYFAIFAAGFGISNTI--RQFRPAAELIRRNRVLSLLALLLILVVVHLNTEVHPYLLA 324

Human   350 DNRHYTFYVWKRVFQRYETVKYLLVPAYIFAGWSIADSLKSKSIFWNLMFFICLFTVIVPQKLLE 414
            ||||||||:|.|::.|:...:|.:.|||:.:...:...|:.....:.|||.:.||.|:..|:|||
  Fly   325 DNRHYTFYIWSRLYGRFWWFRYAMAPAYLLSICVLFCGLRHMPESFKLMFPLSLFLVLCFQRLLE 389

Human   415 FRYFILPYVIYRLNIPLPPTSRLI-------CELSCYAVVNFITFFIFLNKTFQWPNSQDIQRFM 472
            .|||::||:::|||      :|..       .||..:.::|..||:::..|.|.|.|.:..||.:
  Fly   390 LRYFLVPYILFRLN------TRHTRKGYAEWLELGAHLLLNVATFYVYFTKEFYWKNYRTPQRII 448

Human   473 W 473
            |
  Fly   449 W 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALG10	NP_116223.3	DIE2_ALG10	33..427	CDD:282739	133/401 (33%)
Alg10	NP_729680.1	DIE2_ALG10	29..402	CDD:282739	133/401 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152710
Domainoid	1	1.000	213	1.000	Domainoid score	I2750
eggNOG	1	0.900	-	-		E1_KOG2642
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6030
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3381
Isobase	1	0.950	-	0	Normalized mean entropy	S11716
OMA	1	1.010	-	-		QHG55092
OrthoDB	1	1.010	-	-		D404988at33208
OrthoFinder	1	1.000	-	-		FOG0004262
OrthoInspector	1	1.000	-	-		otm41735
orthoMCL	1	0.900	-	-		OOG6_103728
Panther	1	1.100	-	-	O	PTHR12989
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3000
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.720