Protein Alignment MAP4K3 and ppk11

DIOPT Version :10

• Sequence 1: NP_003609.2
• Gene: MAP4K3 / 8491
• HGNCID: 6865
• Length: 894
• Species: Homo sapiens
• Sequence 2: NP_594517.1
• Gene: ppk11 / 2541473
• PomBaseID: SPAC2C4.14C
• Length: 312
• Species: Schizosaccharomyces pombe
• Alignment Length: 324
• Identity: 130/324 - (40%)
• Similarity: 193/324 - (59%)
• Gaps: 26/324 - (8%)

Human    19 IQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGED-FAVVQQEIIMMKDCKHPNIVAYFGSYLR 82
            :|.||.|::|.|::|::|.:.::.|:||:.|:..:| ...:.|||..:.|....:|..|:.|::.
pombe     9 LQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVD 73

Human    83 RDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDN 147
            ..:|||.||:|.|||..|:..::|..||..||.|.|:.|:.|.|||.:||||||||.||||...:
pombe    74 GFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKD 138

Human   148 GHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQP 212
            |.|||||||||.|:.:...|...|:|||:||||||.   ::.|||...|:|::||||.|||..:|
pombe   139 GLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVV---KQTGYNYKADIWSLGITAYELATGEP 200

Human   213 PMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHL 277
            |...:|||:.|.|:.|.:  ||.| ::.|:|.:|..||...|.||||.|.|||.|.:|.|:.::.
pombe   201 PYSGIHPMKVLLLIPKHS--PPSL-ERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKKYC 262

Human   278 TRSLAIELLDKVNNPDHSTYHDFDDDD--PEPLVAVPHRIHSTSRNVREEKTRSEIT--FGQVK 337
            ..:...|::        ::|..:.:.:  ||   |.|:  :||..|  ...|..|:.  ||.|:
pombe   263 PNTSVKEVV--------ASYAKWKESELLPE---ATPY--NSTMGN--SANTIDEVVWDFGTVR 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAP4K3	NP_003609.2	STKc_MAP4K3_like	15..273	CDD:270788	115/254 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	410..536
		CNH	561..874	CDD:214481
ppk11	NP_594517.1	STKc_MST3_like	4..278	CDD:270786	118/282 (42%)