Protein Alignment MAP4K3 and Map4k3

DIOPT Version :10

• Sequence 1: NP_003609.2
• Gene: MAP4K3 / 8491
• HGNCID: 6865
• Length: 894
• Species: Homo sapiens
• Sequence 2: XP_036016462.1
• Gene: Map4k3 / 225028
• MGIID: 2154405
• Length: 935
• Species: Mus musculus
• Alignment Length: 935
• Identity: 858/935 - (91%)
• Similarity: 874/935 - (93%)
• Gaps: 41/935 - (4%)

Human     1 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMM 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMM 65

Human    66 KDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSK 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 KDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSK 130

Human   131 GKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 GKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC 195

Human   196 DLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKK 260
            ||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||
Mouse   196 DLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKK 260

Human   261 RPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSRNVREE 325
            ||.||||||||||||.|||||||||||||||||||||||||||||||||||||||.|||||||||
Mouse   261 RPNAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIPSTSRNVREE 325

Human   326 KTRSEITFGQVKFDPPLRKETEPHHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQGGYFLG 390
            ||||||.||||||||||||||||||||||||||.|||||||||||||||||||||||||...|||
Mouse   326 KTRSEINFGQVKFDPPLRKETEPHHELPDSDGFFDSSEEIYYTARSNLDLQLEYGQGHQSHCFLG 390

Human   391 ANK-----------SLLKSVEEELHQRGHVAHLEDDEGDDDESKHSTLKAKIPPPLPPKPKSIFI 444
            .||           |||||||||||||||||||||||||||:|||||:|||:|||||||||||||
Mouse   391 GNKNCILYNESLARSLLKSVEEELHQRGHVAHLEDDEGDDDDSKHSTMKAKVPPPLPPKPKSIFI 455

Human   445 PQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPPPRLPPHKPVALGNGMSSFQLNGERDGSLC 509
            ||:.||.||.|||||||||.||||||||.||||||||||||.||..||||::||||||||||||.
Mouse   456 PQDTHSAEDGNQGTIKRCPSSGSPAKPSHVPPRPPPPRLPPQKPAVLGNGVNSFQLNGERDGSLY 520

Human   510 QQQNEHRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQY 574
            |||:|.|||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||
Mouse   521 QQQSEQRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQY 585

Human   575 LIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQM 639
            ||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
Mouse   586 LIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSVSGKASQLYSHNLPGLFDYARQM 650

Human   640 QKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEP 704
            |||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Mouse   651 QKLPVAIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEP 715

Human   705 MQKFMLIKHIDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTES 769
            ||||||||||:||:|||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   716 MQKFMLIKHIEFPMPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTES 780

Human   770 D------------------------------TPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRL 804
            :                              .|||:|||||||||||||||||||||||||||||
Mouse   781 EPSVVVRTCNPSTSEVEAGRSGVRDQSELHNAPQTSVTHVTQLERDTILVCLDCCIKIVNLQGRL 845

Human   805 KSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVV 869
            ||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||
Mouse   846 KSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDNTRIFRLLGSDRVVV 910

Human   870 LESRPTDNPTANSNLYILAGHENSY 894
            |||||||||||||||||||||||||
Mouse   911 LESRPTDNPTANSNLYILAGHENSY 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAP4K3	NP_003609.2	STKc_MAP4K3_like	15..273	CDD:270788	255/257 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	410..536		108/125 (86%)
		CNH	561..874	CDD:214481	303/342 (89%)
Map4k3	XP_036016462.1	STKc_MAP4K3_like	15..273	CDD:270788	255/257 (99%)
		CNH	572..915	CDD:214481	303/342 (89%)