Protein Alignment MAP4K3 and Map4k3

DIOPT Version :10

• Sequence 1: NP_003609.2
• Gene: MAP4K3 / 8491
• HGNCID: 6865
• Length: 894
• Species: Homo sapiens
• Sequence 2: XP_038967654.1
• Gene: Map4k3 / 170920
• RGDID: 621280
• Length: 946
• Species: Rattus norvegicus
• Alignment Length: 946
• Identity: 860/946 - (90%)
• Similarity: 876/946 - (92%)
• Gaps: 52/946 - (5%)

Human     1 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMM 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMM 65

Human    66 KDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSK 130
            |||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 KDCKHANIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSK 130

Human   131 GKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 GKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC 195

Human   196 DLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKK 260
            ||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||
  Rat   196 DLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKK 260

Human   261 RPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSRNVREE 325
            |||||||||||||||.|||||||||||||||||||||||||||||||||||||||.|||||||||
  Rat   261 RPTAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIPSTSRNVREE 325

Human   326 KTRSEITFGQVKFDPPLRKETEPHHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQGGYFLG 390
            ||||||.||||||||||||||||||||||||||.|||||:|||||||||||||||||||..||||
  Rat   326 KTRSEINFGQVKFDPPLRKETEPHHELPDSDGFFDSSEEMYYTARSNLDLQLEYGQGHQSNYFLG 390

Human   391 ANK-----------SLLKSVEEELHQRGHVAHLEDDEGDDDESKHSTLKAKIPPPLPPKPKSIFI 444
            .||           |||||||||||||||||||||||||||:|||||||||:|||||||||||.|
  Rat   391 GNKNCILYNESLARSLLKSVEEELHQRGHVAHLEDDEGDDDDSKHSTLKAKVPPPLPPKPKSISI 455

Human   445 PQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPPPRLPPHKPVAL-----------GNGMSSF 498
            ||:.||:||.|||||||||.||||||||.||||||||||||.||..|           |||:|||
  Rat   456 PQDTHSSEDSNQGTIKRCPSSGSPAKPSHVPPRPPPPRLPPQKPAVLGEGGGQIQLSQGNGVSSF 520

Human   499 QLNGERDGSLCQQQNEHRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCAS 563
            |||||||||:.|||:|.|||||||||||||||||||||||||||||||||||||||||||||||:
  Rat   521 QLNGERDGSVHQQQSEQRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCAT 585

Human   564 SWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHN 628
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||
  Rat   586 SWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSVSGKASQLYSHN 650

Human   629 LPGLFDYARQMQKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQ 693
            ||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||
  Rat   651 LPGLFDYARQMQKLPVAIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQ 715

Human   694 TSIVLLEWVEPMQKFMLIKHIDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVN 758
            |||||||||||||||||||||:||:||||||||||||||||||||||||||||||||||||||||
  Rat   716 TSIVLLEWVEPMQKFMLIKHIEFPMPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVN 780

Human   759 PNSTSSWFTESD------------------------------TPQTNVTHVTQLERDTILVCLDC 793
            |||||||||||:                              |||||||||||||||||||||||
  Rat   781 PNSTSSWFTESEPSVVVHTCNPSTSEVVAGRAGVRHQSELHNTPQTNVTHVTQLERDTILVCLDC 845

Human   794 CIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRI 858
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||
  Rat   846 CIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDNTRI 910

Human   859 FRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY 894
            ||||||||||||||||||||||||||||||||||||
  Rat   911 FRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAP4K3	NP_003609.2	STKc_MAP4K3_like	15..273	CDD:270788	255/257 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	410..536		108/136 (79%)
		CNH	561..874	CDD:214481	305/342 (89%)
Map4k3	XP_038967654.1	STKc_MAP4K3_like	15..273	CDD:270788	255/257 (99%)
		CNH	583..926	CDD:214481	305/342 (89%)