DRSC/TRiP Functional Genomics Resources

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Protein Alignment RGS5 and Axn

DIOPT Version :9

Sequence 1:NP_001241678.1 Gene:RGS5 / 8490 HGNCID:10001 Length:185 Species:Homo sapiens
Sequence 2:NP_733336.1 Gene:Axn / 43565 FlyBaseID:FBgn0026597 Length:745 Species:Drosophila melanogaster


Alignment Length:138 Identity:37/138 - (26%)
Similarity:61/138 - (44%) Gaps:6/138 - (4%)


- Green bases have known domain annotations that are detailed below.


Human    45 EKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFS--EENLEFWIACEDYKKIKSPA 107
            |..|.|.|.|....|.|..:|:.||::..|:..||.:::.|..  .::|.|:.|||..|:...| 
  Fly    35 EGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDP- 98

Human   108 KMAEKAKQIYEEFIQTEAPKEVGLWVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLP 172
               ||.|||.....:.....::.:..::....|.|.....:..|...||..|:.:...:..:..|
  Fly    99 ---EKIKQIIGAIYRFLRKSQLSISDDLRAQIKAIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYP 160

Human   173 RFVRSEFY 180
            .|:.||.|
  Fly   161 TFLCSEMY 168

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RGS5NP_001241678.1 RGS_RGS5 65..182 CDD:188672 30/118 (25%)
AxnNP_733336.1 RGS 55..170 CDD:295367 30/118 (25%)
Axin_b-cat_bind 494..543 CDD:285982
DIX 665..739 CDD:279160
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3589
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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