Protein Alignment CBR4 and CG31546

DIOPT Version :10

• Sequence 1: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Sequence 2: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 82/269 - (30%)
• Similarity: 126/269 - (46%)
• Gaps: 46/269 - (17%)

Human     3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG---AKAAAGDLGGDHLAFSCDVAKEHDVQ 64
            ||..:.|.:.|||.|.|::.::.|..||::.|..||   .......:|.:....:.|:.|..:::
  Fly    14 KVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEPYGIAGDLLKPPEIE 78

Human    65 NTFEE-LEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN----------LLGSMLTCKAA 118
            ....: .|::.|:::.|||.|||...|.|..|:.......:..|          ||..:|.||
  Fly    79 CIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANVRSGFYLTKLLLPQLLQCK-- 141

Human   119 MRTMIQQQGGSIVNVGHRREMLLHKRSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 183
                     ||||||.          |:.||:.......|:.||..:..|:|:||.::..:.:||
  Fly   142 ---------GSIVNVS----------SVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRV 187

Human   184 NVVAPGFVHTDMTK--DLKE-------EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 237
            |.|.||.:.|::.|  .:.|       ||.||...|||.||..|||.|:.||..  :.::||..|
  Fly   188 NAVNPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTL 252

Human   238 VVDGGLQLI 246
            .||||.|::
  Fly   253 PVDGGKQVM 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	80/264 (30%)
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	82/267 (31%)