Protein Alignment CBR4 and CG12171

DIOPT Version :10

• Sequence 1: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Sequence 2: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 88/257 - (34%)
• Similarity: 124/257 - (48%)
• Gaps: 28/257 - (10%)

Human     2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAFSCDVAKEHD 62
            |||..|.|.|.|||...:.|:|:.|..|.::.|||:.....|..:    |...|..:.|:..|.|
  Fly     6 DKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESD 70

Human    63 VQNTFE-ELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126
            ||.... .|.|| ||::.|||.|||...|.:..|..|.....::||:.............:|:.:
  Fly    71 VQGIVSATLAKH-GRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK 134

Human   127 GGSIVNVGHRREMLLHKRSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 191
             |:||||.          |:.|::...|...|:.||..:..|:|.:|.|:|.|.:|||.|.||.:
  Fly   135 -GNIVNVS----------SVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVI 188

Human   192 HTDMTK----DLKE-----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 242
            .|::.:    |.:.     ||.|....|||.||..|||.|:.||.  |:.:.||..|.||||
  Fly   189 ITELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	87/256 (34%)
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	88/257 (34%)