Protein Alignment CBR4 and CG8757

DIOPT Version :10

• Sequence 1: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Sequence 2: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Alignment Length: 246
• Identity: 68/246 - (27%)
• Similarity: 120/246 - (48%)
• Gaps: 33/246 - (13%)

Human     2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHL----AFSCDVAKEHD 62
            :||..|.|.|.|||.|..:.:...|..:..:||..|..:.....|..:..    |..||:.:|..
  Fly     6 NKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDITQEDQ 70

Human    63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED---MVSQLHTNLLGSMLTCKAAMRTMIQ 124
            |...|:...:.||.|:.||:.|||...|.|  ::.:|   |.|.:.||::|::...:.:.|:| :
  Fly    71 VLKAFDWTCRQLGGVDVLVSNAGIIGTGEL--SERDDGPAMRSTIETNIMGTVYCVRESFRSM-K 132

Human   125 QQG--GSIVNVGHRREMLLHKRSIVGLK-GNSGQ-----SVYSASKGGLVGFSRALAKEVARKK- 180
            ::|  |.:|.|          .|:.|.: .|.|.     ::|.|:|..|...:....:|..|.|
  Fly   133 RRGTEGHVVIV----------NSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKT 187

Human   181 -IRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP 230
             :||:.|:||.|.|.:..:..:..:|:::|:.|   :.:||.||::.:.:|
  Fly   188 AVRVSTVSPGIVDTVILPEQIQGIIKQHMPMLR---SDDVADAVLWAIGTP 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	68/245 (28%)
CG8757	NP_648664.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	68/246 (28%)