Protein Alignment CBR4 and CG7322

DIOPT Version :10

• Sequence 1: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Sequence 2: NP_573333.2
• Gene: CG7322 / 32880
• FlyBaseID: FBgn0030968
• Length: 242
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 76/272 - (27%)
• Similarity: 109/272 - (40%)
• Gaps: 73/272 - (26%)

Human     3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG-----------DLGG-------- 48
            ||..|.|...|||:|:.:.:|..|..:..:||..|..:....           ||.|
  Fly     8 KVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDPVHIQPLQLDLSGWQAVREGL 72

Human    49 ------DHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN 107
                  |.|..:..||    :...||||.:.....:|.||...       |...|:.::.:|
  Fly    73 AKVPLLDGLVNNAGVA----IIKPFEELTEQDFDTHFDVNIKA-------VFNVTQSLLPRL--- 123

Human   108 LLGSMLTCKAAMRTMIQQQGGSIVNVGHRREMLLHKRSIVGLKGNSGQSVYSASKGGLVGFSRAL 172
                             :.|.|||||.          ||...:...|.:.|||:|..|...:::|
  Fly   124 -----------------KDGASIVNVS----------SIASSRSFGGHTAYSATKAALDSLTKSL 161

Human   173 AKEVARKKIRVNVVAPGFVHTDMTKD-----LKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESP 230
            |.|:..:|||||.|.|..|.|.|..|     .|...|..:|||.||.|..||..|..:||  :|.
  Fly   162 ALELGPRKIRVNSVNPTVVLTKMGADNWSDPAKSGPLLAHIPLNRFCEVQEVVDATGYLLSSKSS 226

Human   231 YITGHVLVVDGG 242
            ::.||.::::||
  Fly   227 FVNGHHILLEGG 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	76/272 (28%)
CG7322	NP_573333.2	XR_like_SDR_c	1..242	CDD:187609	76/272 (28%)