Protein Alignment ZNF503 and noc

DIOPT Version :10

• Sequence 1: NP_116161.2
• Gene: ZNF503 / 84858
• HGNCID: 23589
• Length: 646
• Species: Homo sapiens
• Sequence 2: NP_476917.1
• Gene: noc / 34847
• FlyBaseID: FBgn0005771
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 183/659 - (27%)
• Similarity: 237/659 - (35%)
• Gaps: 230/659 - (34%)

Human    79 MLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIG---------------KPDP 128
            ::|......|.|:||.|||:|      :||||||||||||||||||               |..|
  Fly    10 VVTIGNNQYLQPDYLAPLPTT------MDAKKSPLALLAQTCSQIGADSSAVKPLLAMDKNKTKP 68

Human   129 SPSSKLSSVASNGG-----GAGGAGGGAAGDK---------------DTKSGPLKL-------SD 166
            ...|..|:.:|:.|     .|....|.|...|               :|.:|.:||       :.
  Fly    69 GACSSSSNSSSSSGSAEISAAKSPSGQAKSPKSSTPISSTATSASLSNTSTGEIKLAFKPYETNV 133

Human   167 IGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTG---- 227
            :..::::|||..|...::...|              ...:|..:..||||.:....||..|
  Fly   134 LSHQNQNSFKSSSSLDAEPTRP--------------SSKNSSSAQERVPSRSKSNATPTDGGKAE 184

Human   228 ----SPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGG 288
                ..|||....||.|. |..|.:|   ..:...:|.....||.
  Fly   185 ISAHDSSSSRKTVSPSGS-SQRGASP---IVRSGMEVLNNANGTA-------------------- 225

Human   289 GINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLP 353
                   |||      |.:.|....::.:::....:.|...:.| |.|..|     ||......|
  Fly   226 -------QHP------KEMSSMAAAAAAAAAAYKAAGPYGLNPL-SALCCP-----PGMEQHANP 271

Human   354 PAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASP 418
            .....:.|..:..:|                       |.||.||.|......|.|..  ||...
  Fly   272 AFRPPFAGGFSHHHA-----------------------AMLAVAANGGYPGGAPGGGP--AGQPN 311

Human   419 PSV------------MTASLCRDPYC----LSYHCASHLAGA--AAASASCAHDPAAAAAALKSG 465
            |.:            ....:|:||||    .|.|....|.||  .|....|.|.....|.|..:|
  Fly   312 PYISYQRIKTPAGGEAIVPVCKDPYCQGCPYSAHTQQMLMGAPCPAGCTQCEHQKYGLAMASAAG 376

Human   466 YPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFA 530
            .|   |.||    :|...|||||.|.....|                |::|:||..:..|.|||.
  Fly   377 LP---PAHP----YSQAAAAAAANAAAARSA----------------PYVCSWVVGDAYCGKRFQ 418

Human   531 TSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTL----ALR- 590
            ||:||.|||||||               .:|:..||||.|    :..|.|....|||    |||
  Fly   419 TSDELFSHLRTHT---------------GNLSDPAAAAAA----LAQSQAQSLLGTLFPPSALRA 464

Human   591 -------SPHHALGLSSRYHPYSKSPLPTPGA----PVP-------------VPAATGPYYSPYA 631
                   ||..|...::|||||:|   |.|||    |.|             ..||.||||||||
  Fly   465 GYPTPPLSPMSAAAAAARYHPYAK---PPPGALAGGPSPFGAAGAFNPAAAAAAAALGPYYSPYA 526

Human   632 LYGQRLTTA 640
            :||||:..|
  Fly   527 MYGQRMGAA 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF503	NP_116161.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70
		SP1-4_N	107..>140	CDD:425404	22/47 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..332		49/260 (19%)
		nlz1	355..415	CDD:403564	10/59 (17%)
		C2H2 Zn finger	516..542	CDD:275368	15/25 (60%)
noc	NP_476917.1	zf-C2H2	402..430	CDD:395048	15/27 (56%)
		C2H2 Zn finger	404..430	CDD:275368	15/25 (60%)