DRSC/TRiP Functional Genomics Resources

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Protein Alignment FCRLA and Fcrla

DIOPT Version :9

Sequence 1:NP_001171795.2 Gene:FCRLA / 84824 HGNCID:18504 Length:365 Species:Homo sapiens
Sequence 2:NP_001153687.1 Gene:Fcrla / 98752 MGIID:2138647 Length:353 Species:Mus musculus


Alignment Length:371 Identity:246/371 - (66%)
Similarity:275/371 - (74%) Gaps:32/371 - (8%)


- Green bases have known domain annotations that are detailed below.


Human     1 MKLGCVLMAWALYLSLGVLWVAQMLLAAGCHAAASFETLQCEGPVCTEESSCHT--------ED- 56
            |||.|.|..||||:...||...||||     ||||.|||:|||.|.||:.||..        || 
Mouse     1 MKLSCTLTQWALYVCPAVLLATQMLL-----AAASSETLKCEGLVSTEQGSCQAAAEEDEGDEDD 60

Human    57 -DLTDAREAGFQVKAYTFSEPFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYR 120
             |:|.:.|||||.|.||||:||||.||||||||||||..:||||.|||.|:||||||||||.|||
Mouse    61 GDMTQSSEAGFQFKGYTFSKPFHLSVSYDWLILQGPATLIFEGDTLVLHCRAWQDWPLTQVIFYR 125

Human   121 DGSALGPPGPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPS 185
            :|||||||||..|||||:|||:|.|||||||||:|||||..|.||.|||||||||.||:|:|:||
Mouse   126 EGSALGPPGPKSEFSITMVQKSDGGHYHCSGIFRSPGPGSREAASPVAITVQELFAAPVLKALPS 190

Human   186 AEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHSGSYWCEAAT 250
            :|||.|..:||||||||.|||||:|||||||||||.:..||:|||.:||.|||:|||||||||.|
Mouse   191 SEPQEGGSVTLSCQTKLALQRSASRLLFSFYKDGRSLSVRGVSSELKIPKASEEHSGSYWCEAVT 255

Human   251 EDNQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKSAAPGTAPEEAPGPLPPPPTPSSEDPGFSSP 315
            ||.|:.||||||||.||             |.||..|..|.|.||.|||||||..|:|.|.||| 
Mouse   256 EDRQISKQSPQLEIWVQ-------------ALQKPTASETPPTEALGPLPPPPASSAEQPRFSS- 306

Human   316 LGMPDPHLYHQMGLLLKHMQDVRVLLGHLLMELRELSGHRKPGTTK 361
               |||||:|||.||||.:||||.|||||:||||:||.:.||||||
Mouse   307 ---PDPHLHHQMQLLLKQIQDVRALLGHLVMELRDLSVYLKPGTTK 349

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FCRLANP_001171795.2 Ig 85..152 CDD:353325 53/66 (80%)
Ig_2 177..266 CDD:316418 65/88 (74%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 265..319 23/53 (43%)
FcrlaNP_001153687.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 47..66 5/18 (28%)
Ig 90..176 CDD:299845 67/85 (79%)
IG_like 102..>154 CDD:214653 41/51 (80%)
Ig_3 182..253 CDD:290638 51/70 (73%)
IG_like 189..262 CDD:214653 53/72 (74%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 276..311 22/38 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C83953373
Domainoid 1 1.000 144 1.000 Domainoid score I35217
eggNOG 00.000 Not matched by this tool.
HGNC 1 1.500 - -
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H13106
Inparanoid 1 1.050 475 1.000 Inparanoid score I12599
Isobase 00.000 Not matched by this tool.
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG34798
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0015690
OrthoInspector 1 1.000 - - oto113583
orthoMCL 1 0.900 - - OOG6_128265
Panther 1 1.100 - - LDO PTHR11481
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X79
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
1414.400

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