DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FCRLA and si:cabz01036006.1

DIOPT Version :9

Sequence 1:	NP_001171795.2	Gene:	FCRLA / 84824	HGNCID:	18504	Length:	365	Species:	Homo sapiens
Sequence 2:	XP_021333347.1	Gene:	si:cabz01036006.1 / 563900	ZFINID:	ZDB-GENE-160113-146	Length:	624	Species:	Danio rerio

Alignment Length:	280	Identity:	76/280 - (27%)
Similarity:	108/280 - (38%)	Gaps:	82/280 - (29%)

- Green bases have known domain annotations that are detailed below.

Human    38 TLQCEGPVCTEE---SSCHTEDDLTD-AREAGFQVKAYTFS-----------------EPFHLIV 81
            ||.||.|..:..   |.....|.|:| :|.||   .:||.|                 ||
Zfish   175 TLICEVPGSSTGWTFSWFRDADHLSDSSRGAG---GSYTLSPAALQHTGVYTCRAERGEP----- 231

Human    82 SYD---------W---------LILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALGPP 128
            :|.         |         |:|.......|..|.|.|.|.: ..|.:.:.|...........
Zfish   232 AYSSQNSSAQPLWVTGVSASVRLVLNASRSQHFSSDSLSLSCDS-AGWTVRRYTHTNTQDCSAQT 295

Human   129 GPNREFSITVVQKADSGHYHC---SGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQ- 189
            |...|  |..:..:|:|.|.|   ||..:.|          :.|||.:   .|::.| .||:|.
Zfish   296 GSTCE--IQSLSTSDTGVYWCESESGEKRHP----------LNITVHD---GPVILA-SSADPVI 344

Human   190 AGSPMTLSCQTKLPLQRS--AARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHSGSYWCEAATED 252
            .|..:||.|     |.||  ::.|...|||||.::|:: .:.|..|||.|:...|.|:|:  ||.
Zfish   345 EGETLTLHC-----LHRSTISSILTADFYKDGLLIQNQ-TTGEMSIPTVSKSDEGFYYCK--TES 401

Human   253 NQVWKQSPQLEIRVQGASSS 272
                .:||...|.|:.:|.|
Zfish   402 ----IESPHSWISVRASSPS 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FCRLA	NP_001171795.2	Ig	85..152	CDD:353325	18/78 (23%)
		Ig_2	177..266	CDD:316418	32/91 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	265..319		3/8 (38%)
si:cabz01036006.1	XP_021333347.1	Ig_2	43..151	CDD:316418
		Ig_3	160..227	CDD:316449	15/54 (28%)
		Ig	335..>397	CDD:325142	25/68 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277104at7742
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9806
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920