DRSC/TRiP Functional Genomics Resources

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Protein Alignment FCRLA and Lac

DIOPT Version :9

Sequence 1:NP_001171795.2 Gene:FCRLA / 84824 HGNCID:18504 Length:365 Species:Homo sapiens
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:219 Identity:44/219 - (20%)
Similarity:78/219 - (35%) Gaps:54/219 - (24%)


- Green bases have known domain annotations that are detailed below.


Human    83 YDWLILQGPAKPVF--EGDLLVLRCQAWQDWPLTQVTFYRDGSALGPPGPNREFSITVVQKADSG 145
            |:.|.|:..:.|||  .|..||::..             |......|.....:..|..:|:.|:|
  Fly    58 YNVLFLKTDSDPVFLSTGSTLVIKDS-------------RFSLRYDPNSSTYKLQIKDIQETDAG 109

Human   146 HYHCSGIFQSPGPGIPETASVVAITVQELFPAPIL--RAVPSAEPQAGSPMTLSCQTKLPLQRSA 208
            .|.|..:..:    :.:.::.|.::|:.   .|::  .:..|.....||.:.:.|..        
  Fly   110 TYTCQVVIST----VHKVSAEVKLSVRR---PPVISDNSTQSVVASEGSEVQMECYA-------- 159

Human   209 ARLLFSFYKDGRIVQSRG------------LSSEFQIPTASEDHSGSYWCEAATEDNQVWK-QSP 260
                 |.|....|...|.            :.:..:|.:..::..|:|:|.|   ||.|.| ...
  Fly   160 -----SGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVA---DNGVSKGDRR 216

Human   261 QLEIRVQGASSSAAP-PTLNPAPQ 283
            .:.:.|:.|.....| |.|..|.|
  Fly   217 NINVEVEFAPVITVPRPRLGQALQ 240

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
FCRLANP_001171795.2 Ig 85..152 CDD:353325 16/68 (24%)
Ig_2 177..266 CDD:316418 18/103 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 265..319 7/20 (35%)
LacNP_523713.2 IG_like 36..131 CDD:214653 18/89 (20%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353