DRSC/TRiP Functional Genomics Resources

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Protein Alignment FCRLA and Nrg

DIOPT Version :9

Sequence 1:NP_001171795.2 Gene:FCRLA / 84824 HGNCID:18504 Length:365 Species:Homo sapiens
Sequence 2:NP_001245581.1 Gene:Nrg / 31792 FlyBaseID:FBgn0264975 Length:1309 Species:Drosophila melanogaster


Alignment Length:260 Identity:59/260 - (22%)
Similarity:96/260 - (36%) Gaps:69/260 - (26%)


- Green bases have known domain annotations that are detailed below.


Human    97 EGDLLVLRCQAWQDWPLTQVTFY----RDGS---------ALGPPGPNREFSITVVQKADSGHYH 148
            ||:..:|:|.|...:|...|.:.    .|||         .|.|.| |..||....:.|.|..|:
  Fly   147 EGEPFMLKCAAPDGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEG-NLWFSNVTREDASSDFYY 210

Human   149 -CS--GIFQSP---GPGIPETASVVAITVQELFPAPILRAVPSAEPQA--GSPMTLSC---QTKL 202
             ||  .:|:|.   |..:......:.::..:....|:.:.|...:..|  |..|.|.|   .|.|
  Fly   211 ACSATS
VFRSEYKIGNKVLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPL 275

Human   203 PLQRSAARLLFSFYKDGRIVQ-----SRG-LSSEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQ 261
            |      :.::|  |||:.:|     ::| ......|...:.|.:|:|.|:.:.           
  Fly   276 P------QTVWS--KDGQRIQWSDRITQGHYGKSLVIRQTNFDDAGTYTCDVSN----------- 321

Human   262 LEIRVQGASSSAAPPTLNPAPQKSAAP--GTAPEEAPGPLPPPPTPSSEDPGFS-SPLGMPDPHL 323
               .|..|.|.:....:|..|..:..|  .||.|:             |:..|. ...|:|:|.:
  Fly   322 ---GVGNAQSFSIILNVNSVPYFTKEPEIATAAED-------------EEVVFECRAAGVPEPKI 370

Human   324  323
              Fly   371  370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FCRLANP_001171795.2 Ig 85..152 CDD:353325 21/70 (30%)
Ig_2 177..266 CDD:316418 21/99 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 265..319 12/56 (21%)
NrgNP_001245581.1 Ig 55..128 CDD:299845
IG_like 57..127 CDD:214653
Ig 135..214 CDD:299845 20/67 (30%)
IG_like 141..216 CDD:214653 21/69 (30%)
ig 251..332 CDD:278476 23/102 (23%)
I-set 339..427 CDD:254352 10/45 (22%)
Ig 354..427 CDD:299845 5/17 (29%)
I-set 432..517 CDD:254352
Ig 446..517 CDD:299845
I-set 522..611 CDD:254352
ig 525..609 CDD:278476
FN3 613..707 CDD:238020
FN3 716..807 CDD:238020
fn3 817..905 CDD:278470
FN3 917..1004 CDD:238020
FN3 1041..1111 CDD:238020
Bravo_FIGEY 1155..>1221 CDD:290593
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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