Protein Alignment RAE1 and CG12782

DIOPT Version :10

• Sequence 1: XP_054180126.1
• Gene: RAE1 / 8480
• HGNCID: 9828
• Length: 434
• Species: Homo sapiens
• Sequence 2: NP_611772.2
• Gene: CG12782 / 37685
• FlyBaseID: FBgn0034838
• Length: 336
• Species: Drosophila melanogaster
• Alignment Length: 330
• Identity: 127/330 - (38%)
• Similarity: 182/330 - (55%)
• Gaps: 17/330 - (5%)

Human    96 KDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCW 160
            :|.|:.:.|:|:|..|.|||.:...|.:.||||.|.||.|||| :.:.:||......|...||.|
  Fly    13 QDYELPNPPNDTISALEFSPRSSSWNAICAGSWDNTVRIWEVQ-ADRLVPKVMNSLEGTPFDVTW 76

Human   161 SDDGSKVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTR 225
            :|.|:||:.:........|||.|||..::..|....:|.||: .|   .:.|.||||:::|||.|
  Fly    77 NDSGNKVYLSDSSGQVTEWDLESNQLRKVGLHARAARTCHWV-GP---YLATTSWDKSIRFWDPR 137

Human   226 SSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESP--LKHQHRCVAIFK 288
            ::..:..::||:|.|.|||:..:||||..:|.::.|.|...|.|..|::||  ...|.|.||:
  Fly   138 AAIELTRMELPDRSYAADVLNDVAVVACGDRSILAYTLRGGPVEQGRMKSPGESNTQVRSVAL-- 200

Human   289 DKQNKP-TGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHG 352
             .||:. |.:.:....|.|   :.........:|..:|||   ...|...|:||||.:..:.|..
  Fly   201 -HQNRDLTSWLIAKTNGMV---FDQSMAHRTVSFPIRCHR---RENSGILDVYAVNEVKVNMVTQ 258

Human   353 TLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKN 417
            .:|||||||.|.|||...|:||..|:...|||:.|..:.:|.:||||..||||||||:.:...|.
  Fly   259 HIATVGSDGVFCFWDSQMRSKLLESKVHPQPITKCAISGDGKLFAYALGYDWSKGHEYSDSSIKP 323

Human   418 YIFLR 422
            :||||
  Fly   324 HIFLR 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAE1	XP_054180126.1	WD40	<105..401	CDD:441893	111/298 (37%)
		WD40 repeat	108..150	CDD:293791	19/41 (46%)
		WD40 repeat	156..191	CDD:293791	13/34 (38%)
		WD40 repeat	196..234	CDD:293791	13/37 (35%)
		WD40 repeat	240..274	CDD:293791	14/33 (42%)
		WD40 repeat	281..324	CDD:293791	9/43 (21%)
		WD40 repeat	342..392	CDD:293791	22/49 (45%)
CG12782	NP_611772.2	WD40	25..303	CDD:475233	106/291 (36%)
		WD40 repeat	26..64	CDD:293791	18/38 (47%)
		WD40 repeat	71..101	CDD:293791	11/29 (38%)
		WD40 repeat	109..146	CDD:293791	13/40 (33%)
		WD40 repeat	195..235	CDD:293791	9/45 (20%)
		WD40 repeat	242..272	CDD:293791	14/29 (48%)