DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NAA11 and CG31730

DIOPT Version :9

Sequence 1:	NP_116082.1	Gene:	NAA11 / 84779	HGNCID:	28125	Length:	229	Species:	Homo sapiens
Sequence 2:	NP_723799.1	Gene:	CG31730 / 318920	FlyBaseID:	FBgn0051730	Length:	162	Species:	Drosophila melanogaster

Alignment Length:	154	Identity:	51/154 - (33%)
Similarity:	81/154 - (52%)	Gaps:	9/154 - (5%)

- Green bases have known domain annotations that are detailed below.

Human     2 NIRNAQPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSY--IAEDEDGKIVGYVLAKMEEEP 64
            :.|..:.|||..:.......|.|.|.:.:::.|.|.:|.||.  ||...||:.:||:..:.:.:.
  Fly     3 SFREMRFDDLFKINSLVFDALTEVYSLTFFVKHFLEFPGLSQIAIAPGPDGRPMGYIFGQYQVKR 67

Human    65 DDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENF-NAKYVSLHVRKSNRPALHLYSNTLNF 128
            :..|:||:.:|.|...:||||||..|||  ...|:.:. .|.||:|.:|.|||.|..||: :|.:
  Fly    68 NQDPYGHVAALTVSPEYRRLGLATALMD--FFFMVSDLKGASYVNLFMRISNRAAYQLYT-SLGY 129

Human   129 QISEVEPKYYAD---GEDAYAMKR 149
            ...:....||.|   .|.||.:::
  Fly   130 AHRQTFLDYYPDEPKPESAYELRK 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAA11	NP_116082.1	RimI	1..149	CDD:223532	51/152 (34%)
		Interaction with NAA15. /evidence=ECO:0000250	1..58		18/57 (32%)
		Acetyltransf_1	47..122	CDD:278980	28/75 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..229
CG31730	NP_723799.1	rimI	9..141	CDD:273701	46/134 (34%)
CG31730	NP_723799.1	Acetyltransf_1	52..129	CDD:278980	31/79 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S458
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100590
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.660