back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment OGT and TFC4

DIOPT Version :10

Sequence 1:	NP_858058.1	Gene:	OGT / 8473	HGNCID:	8127	Length:	1046	Species:	Homo sapiens
Sequence 2:	NP_011561.3	Gene:	TFC4 / 852938	SGDID:	S000003279	Length:	1025	Species:	Saccharomyces cerevisiae

Alignment Length:	577	Identity:	103/577 - (17%)
Similarity:	184/577 - (31%)	Gaps:	220/577 - (38%)

- Green bases have known domain annotations that are detailed below.

Human    82 IKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME-GAVQA 145
            ||::.....||..||::|:.:|:|.:....:         |:..::|       |.|.| ..:.|
Yeast   155 IKKDARNFAAYETLGDIYQLQGRLNDCCNSW---------FLAAHLN-------ASDWEFWKIVA 203

Human   146 YVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNL---GCVFNAQGEI 207
            .:||     ||..||              :|..|:.:.|...|   :.|.::   ..::...|::
Yeast   204 ILSA-----DLDHVR--------------QAIYCFSRVISLNP---MEWESIYRRSMLYKKTGQL 246

Human   208 WLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI----FDR---------------------AVAA 247
            ..|:..|::....:|  .||     |:|:|..|    :||                     .:||
Yeast   247 ARALDGFQRLYMYNP--YDA-----NILRELAILYVDYDRIEDSIELYMKVFNANVERREAILAA 304

Human   248 YLRALSLSPNHAVVHGNLA----------------------------CVYYEQGLIDLAIDTY-- 282
            ...||..|...:...|..|                            |:.::...:::..:.:
Yeast   305 LENALDSSDEESAAEGEDADEKEPLEQDEDRQMFPDINWKKIDAKYKCIPFDWSSLNILAELFLK 369

Human   283 ---------------------RRAIELQPHFPD--AYCN--LANALKEKGSVAEAEDCYNTALRL 322
                                 |.:.....|.||  .:.|  ..|:..:....||.|..||..:
Yeast   370 LAVSEVDGIKTIKKCARWIQRRESQTFWDHVPDDSEFDNRRFKNSTFDSLLAAEKEKSYNIPI-- 432

Human   323 CPTHADSLNNLANIKREQGNIEEAVR----LYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMH 383
                 |....|..::....|:.||:.    ||.   |.|.:.|..:...|:.|.:..|.:||:..
Yeast   433 -----DIRVRLGLLRLNTDNLVEALNHFQCLYD---ETFSDVADLYFEAATALTRAEKYKEAIDF 489

Human   384 YKEAIRISP-TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIH-------- 439
            :...:.:.. ...|.:..:....||::..:.|.:.|..||:..|...|...:||.::
Yeast   490 FTPLLSLEEWRTTDVFKPLARCYKEIESYETAKEFYELAIKSEPDDLDIRVSLAEVYYRLNDPET 554

Human   440 -------------------------KDSGNIPEAIAS--------YRTALKLKPDFPDAYCNLAH 471
                                     :.|.|....|:|        :||..|.|.
Yeast   555 FKHMLVDVVEMRKHQVDETLHRISNEKSSNDTSDISSKPLLEDSKFRTFRKKKR----------- 608

Human   472 CLQIVCDWTDYD------ERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKA 522
                    |.||      ||.:::.:.|.|:.||.:          .:.|:.|..:|
Yeast   609 --------TPYDAERERIERERRITAKVVDKYEKMK----------KFELNSGLNEA 647

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.