DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment LNX1 and CG10939

DIOPT Version :9

Sequence 1:NP_001119800.1 Gene:LNX1 / 84708 HGNCID:6657 Length:728 Species:Homo sapiens
Sequence 2:NP_524712.1 Gene:CG10939 / 44155 FlyBaseID:FBgn0010620 Length:296 Species:Drosophila melanogaster


Alignment Length:262 Identity:63/262 - (24%)
Similarity:92/262 - (35%) Gaps:80/262 - (30%)


- Green bases have known domain annotations that are detailed below.


Human   490 RSNTPKPLHP--TITCHEKVVNIQKDPG-ESLGMTVAGGASHREWDLPIYVISVEPG---GVISR 548
            ::.||..|.|  |.|||     |.|.|. :..|..:     |.|        .|:||   |.:..
  Fly     8 KTPTPPTLPPGVTKTCH-----IVKRPDFDGYGFNL-----HSE--------KVKPGQFIGKVDA 54

Human   549 D-----GRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVL-------KALEVKEYEPQEDC 601
            |     ..:|.||.:|.|:||.:...:..:.||.:|..::.:.|       ||||||...|    
  Fly    55 DSPAEAAGLKEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLLIDVDGKALEVKPASP---- 115

Human   602 SSPAALDSNHNMAPPSDWSPSWVMWLELPRCLYNCKDIVL----RRNTAGSL------------- 649
              |||..:.:..|..:.:..:   ..|:|....|...|.:    |.:.|.|:             
  Fly   116 --PAAACNGNGSASQNGYEGT---KQEMPGASANISSISMVSTKRSSNASSIQSGSTMNASDLDV 175

Human   650 ---GFCIVGG------YEEYNGNKPFFIKSIVEGT-------PAYNDGRIRCGDILLAVNGRSTS 698
               |...|..      ....||:||  ...|...|       |:.....|.....:...||..|:
  Fly   176 VDRGIPAVAAPVAITPPPVQNGSKP--SSPINNNTLMSTPPPPSATKAGINNNGSVYNTNGNGTN 238

Human   699 GM 700
            ||
  Fly   239 GM 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LNX1NP_001119800.1 mRING-HC-C3HC3D_LNX1 38..79 CDD:319693
modified RING-HC finger (C3HC3D-type) 41..78 CDD:319693
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 178..214
NPXY motif 181..184
Interaction with MAGEB18. /evidence=ECO:0000269|PubMed:20864041 186..244
PDZ_signaling 272..355 CDD:238492
PDZ_signaling 380..460 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 475..494 0/3 (0%)
PDZ_signaling 505..588 CDD:238492 22/98 (22%)
PDZ_signaling 637..721 CDD:238492 19/97 (20%)
CG10939NP_524712.1 PDZ_signaling 20..101 CDD:238492 26/98 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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