Protein Alignment GPT2 and Kyat

DIOPT Version :10

• Sequence 1: XP_047290768.1
• Gene: GPT2 / 84706
• HGNCID: 18062
• Length: 554
• Species: Homo sapiens
• Sequence 2: NP_650121.1
• Gene: Kyat / 41433
• FlyBaseID: FBgn0037955
• Length: 450
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 98/518 - (18%)
• Similarity: 176/518 - (33%)
• Gaps: 157/518 - (30%)

Human    40 ERSRRERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQ 104
            :||.||: ..|:::..|..|::        ::..::...||......:.|.|      |.||..:
  Fly    13 KRSLREQ-FQLQALRHQQTAIK--------MEKFDLPKRLQGSTPSVWNEYI------ALAMQYK 62

Human   105 PITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGEAPTCQAPRREMNECSQAAPA 169
            |:             ||  ...||:||                       ||....:..:..|..
  Fly    63 PL-------------NL--GQGFPDDA-----------------------APEYVTHSLADIAKE 89

Human   170 SSGGSCMRMGSYSASQG----VNCIREDVAAYITRRDGGVPADP-DNIYLTTGASDGI-STILKI 228
            .:    ..:..|:...|    ||.:.:..:..:     |...:| .:|.:|:||.:.: |||:
  Fly    90 QN----PLLHQYTRGYGHVRLVNALSKLYSGLV-----GKELNPLSDILITSGAYEALYSTIM-- 143

Human   229 LVSGGGKSRTG--VMIPIPQYPLYSAVISELDAI----------------QVNYYLDEENCWALN 275
                 |....|  |:|..|.:..|..::.....:                ..::.||:
  Fly   144 -----GHVDVGDEVIIIEPFFDCYEPMVKMAGGVPRFVPLKLRKTEGPISSADWVLDD------- 196

Human   276 VNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSP 340
                  |..|:..:...|::.:..|.||.|:|.:||.:|.:.....:..:..::||||:..|:.
  Fly   197 ------AEFESLFNSKTKMIILNTPHNPIGKVFNRKELERIAELCRKWNVLCVSDEVYEWLVFD- 254

Human   341 DCRFHSFKKVLYEMGPE----------YSSNVELASFHSTSKGYMGECGYRGGYMEVI-NLHPEI 394
                          |.|          :...:.|.|...|......:.|:..|..|:| ||
  Fly   255 --------------GAEHIRICTLPGMWDRTITLGSAGKTFSVTGWKIGWAYGPAELIRNL---- 301

Human   395 KGQLVKLLSVRLCP-PVSGQAAMDIVVNPPVAGEESFE-QFSR--EKESVLGNLAKKAKLTEDL- 454
              |:|...||..|| |:....|            .||| :.:|  :.||...:|.::.|...|.
  Fly   302 --QMVHQNSVYTCPTPLQEGVA------------RSFEVELARLGQPESYFLSLPRELKQKRDFM 352

Human   455 --FNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGF 515
              |....|:.....:|..:........|..::.:.......|..:...:.:..|:..:|.|.|
  Fly   353 AKFLSESGMRPTIPEGGYFMLADWSPLAGKIDLSSEPDKHRDYKFTKWMTKNMGLQGIPPSAF 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPT2	XP_047290768.1	PTZ00377	48..554	CDD:240391	94/510 (18%)
Kyat	NP_650121.1	PRK08912	56..449	CDD:181580	87/460 (19%)