Protein Alignment GPT2 and CG6321

DIOPT Version :10

• Sequence 1: XP_047290768.1
• Gene: GPT2 / 84706
• HGNCID: 18062
• Length: 554
• Species: Homo sapiens
• Sequence 2: NP_648426.1
• Gene: CG6321 / 39233
• FlyBaseID: FBgn0036117
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 418
• Identity: 89/418 - (21%)
• Similarity: 152/418 - (36%)
• Gaps: 124/418 - (29%)

Human   181 YSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIP 245
            |..:.|...:|.:::.|.|..... |.:.:::.:|||||.|:..:|..::...|      .:.:.
  Fly    68 YGPTSGTFEVRREISTYFTEMFKS-PVNCEDLIITTGASHGLHILLSTMLDFEG------FVFVD 125

Human   246 QYPLYSAVISELDAIQ-------VNYYLDEENCWALNVNELRRAVQEAKDHCDPK-----VLCII 298
            :|....|    ||:|:       |...|:::   .:::.:|...|.:.:.....|     ...|.
  Fly   126 EYTYMIA----LDSIKHFSTVTIVPVKLNDD---GVDLKDLEEKVSKRRFQSKKKEFWGIYYTIP 183

Human   299 NPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVE 363
            ...||||.:.|.:....::..|......::.|:||  |:.:            |...|.:|..:.
  Fly   184 TYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVY--NILN------------YGETPTHSRLLS 234

Human   364 L-----ASF--HSTSKGYMGEC---GYRGGYMEV-INLHPEIKGQLVKLLSVRLCPPVSGQAAMD 417
            .     |:|  |..|.|...:.   |.|.|::|| ..|.|.:.|              ||.|...
  Fly   235 YDDRNDANFAGHVISNGSFSKILGPGVRLGWLEVPPRLKPILDG--------------SGFATSG 285

Human   418 IVVNPPVAG---------------EESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPL- 466
            ...|...:|               .||:|.:   ||.:|..       |:.|.:::|  .|..|
  Fly   286 GCFNNYTSGIVGSLFELKLAQKQISESYEAY---KERMLAT-------TQVLRDELP--DCCKLV 338

Human   467 --QGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLL----EETGICVVPGSGF---GQREGTY 522
              .|..:.:.||                ||...|.:.|    |...|..:.|:.|   || .|..
  Fly   339 SPTGGYFIWVRI----------------PDRLDCREFLKYCMENHKIYFIVGTRFSADGQ-SGKQ 386

Human   523 HFRMTI-LPPVEKL----KTVLQKVKDF 545
            .||::| ..|..||    :.:...:||:
  Fly   387 FFRLSIAFYPKSKLVDGARRLCNALKDY 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPT2	XP_047290768.1	PTZ00377	48..554	CDD:240391	89/418 (21%)
CG6321	NP_648426.1	ARO8	<23..414	CDD:440781	88/416 (21%)