Protein Alignment GPT2 and CG1640

DIOPT Version :10

• Sequence 1: XP_047290768.1
• Gene: GPT2 / 84706
• HGNCID: 18062
• Length: 554
• Species: Homo sapiens
• Sequence 2: NP_727696.2
• Gene: CG1640 / 32292
• FlyBaseID: FBgn0030478
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 271/551 - (49%)
• Similarity: 365/551 - (66%)
• Gaps: 51/551 - (9%)

Human    22 RSQSSAAAEASAVLK--------VRPERSRR-----------ERILTLESMNPQVKAVEYAVRGP 67
            :|.::|...|:|..:        ::|...||           .:.|||:::||...|:|||||||
  Fly    56 KSTATATVTAAATSQRHGTSGDFIQPLDVRRSFSTSHKMPSSSKALTLDNINPNFIAMEYAVRGP 120

Human    68 IVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAK 132
            :|::|||||.||::|:||||.:||||||||..||||||:|||||::||.....|||||.:|||.|
  Fly   121 LVIRAGEIEKELEKGVKKPFDQVIRANIGDCHAMGQQPLTFLRQLLALTFETRLLDSPDYPEDVK 185

Human   133 KRARRILQACGGNSLGEAPTCQAPRREMNECSQAAPASSGGSCMRMGSYSASQGVNCIREDVAAY 197
            |||..||..|.|.|                               :|||:.|.|:..:|..||.|
  Fly   186 KRACAILNGCQGQS-------------------------------VGSYTDSAGLEVVRRQVAQY 219

Human   198 ITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQV 262
            |.:||||:.::..:||||.|||.||.:||.::.:..|....|||:||||||||||.|||....:|
  Fly   220 IEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPGVMVPIPQYPLYSATISEYGMTKV 284

Human   263 NYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFL 327
            :|||:||..|:|:..||:|:..|||..|:|:.|.:||||||||||.:|:.||::|.||.:.|:.:
  Fly   285 DYYLEEETGWSLDRKELQRSYDEAKKVCNPRALVVINPGNPTGQVLTRENIEEIIKFAHDNKVLV 349

Human   328 LADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHP 392
            |||||||||||..:.:|.|||||.||||..| .|:|:.||.||||||:||||.|||||||:||.|
  Fly   350 LADEVYQDNVYDKNSKFWSFKKVAYEMGDPY-RNLEMVSFLSTSKGYLGECGIRGGYMEVLNLDP 413

Human   393 EIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQ 457
            ::|..|.|.::..||...:||.|:..:||||..||.|::.:.:|::.:|..|.::|:|.....|.
  Fly   414 KVKAMLTKSITAALCSTTAGQVAVSALVNPPQPGEPSYDLYKKERDGILAALKERAELVHKALNS 478

Human   458 VPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTY 522
            ..|...||:|||||.||:|.||.||:|||:|..||||:||..:|||.:|||:||||||||:.||:
  Fly   479 FEGYKVNPVQGAMYVFPQIEIPPKAIEAAKAKGMAPDVFYAFELLETSGICIVPGSGFGQKPGTW 543

Human   523 HFRMTILPPVEKLKTVLQKVKDFHINFLEKY 553
            |||.||||..:|||.:::|.:.||..|::||
  Fly   544 HFRSTILPQTDKLKLMMEKFRVFHAEFMKKY 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPT2	XP_047290768.1	PTZ00377	48..554	CDD:240391	264/506 (52%)
CG1640	NP_727696.2	PTZ00377	99..575	CDD:240391	264/508 (52%)