Protein Alignment CAT and Cat

DIOPT Version :9

• Sequence 1: NP_001743.1
• Gene: CAT / 847
• HGNCID: 1516
• Length: 527
• Species: Homo sapiens
• Sequence 2: NP_536731.1
• Gene: Cat / 40048
• FlyBaseID: FBgn0000261
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 334/503 - (66%)
• Similarity: 403/503 - (80%)
• Gaps: 7/503 - (1%)

Human     5 RDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERI 69
            ||.||:|:..:|..:..... .:|||.|.|:|.|....|||||||:|:|||.|.|||:|||||||
  Fly     4 RDAASNQLIDYKNSQTVSPG-AITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERI 67

Human    70 PERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAV 134
            |||||||||||||||||||||||:|..||:|:.:.|:||:|||||||.||||||||.||||||||
  Fly    68 PERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAV 132

Human   135 KFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFL 199
            |||||||.|||||||||:||||||||||||||:||||||||||||||.|||.:|||||.|||..|
  Fly   133 KFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVCIL 197

Human   200 FSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRD 264
            |||||.|||:.||||||||||||:||.||.:|.|||:|||||||||.|:.|.:|:..||||.|||
  Fly   198 FSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRD 262

Human   265 LFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEV 329
            |:|.|.|.|:||||.||||||:.||:.|.:||||:||||..|:||||||||:||:|||.||||||
  Fly   263 LYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEV 327

Human   330 EQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCM 394
            |||||.|:::.||:|.||||||.||||:|.||||||||||||.|||||||:.::.|:||||.|.:
  Fly   328 EQIAFSPAHLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDGAMNV 392

Human   395 QDNQGGAPNYYPNSFGAPEQQP--SALEHSIQYSGEVRRFNTAN-DDNVTQVRAFYVNVLNEEQR 456
            .|||.|||||:||||..|::.|  .||......:|:|.|:::.: :||..||..|:|:||::..:
  Fly   393 TDNQDGAPNYFPNSFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDKCAK 457

Human   457 KRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEK 504
            |||.:||||||.:|..|:|::||||||:||.|:|   :.|.::.|..|
  Fly   458 KRLVQNIAGHLSNASQFLQERAVKNFTQVHADFG---RMLTEELNLAK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAT	NP_001743.1	catalase_clade_3	68..497	CDD:163712	298/431 (69%)
Cat	NP_536731.1	KatE	10..505	CDD:223824	330/497 (66%)
		catalase_clade_3	66..498	CDD:163712	299/434 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160398
Domainoid	1	1.000	623	1.000	Domainoid score	I175
eggNOG	1	0.900	-	-		E1_COG0753
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	701	1.000	Inparanoid score	I677
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62736
OrthoDB	1	1.010	-	-		D172396at33208
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		otm40368
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	LDO	PTHR11465
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R169
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800