Protein Alignment SMARCA5 and smarca5

DIOPT Version :10

• Sequence 1: NP_003592.3
• Gene: SMARCA5 / 8467
• HGNCID: 11101
• Length: 1052
• Species: Homo sapiens
• Sequence 2: NP_001075098.2
• Gene: smarca5 / 282615
• ZFINID: ZDB-GENE-021125-1
• Length: 1035
• Species: Danio rerio
• Alignment Length: 1052
• Identity: 900/1052 - (85%)
• Similarity: 963/1052 - (91%)
• Gaps: 23/1052 - (2%)

Human     2 SSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEIFDDAS 66
            ||..:.....|.:..|:.||.      .::|..|..|.......:.|.|:.|..|:.:::...
Zfish     6 SSMEQQREEEPSQLDPAGPAE------DDTSENGHDEASDTAMDSEAQSSSPPSAKGKDLLGG-- 62

Human    67 PGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRIKKDE 131
                         ||||:||||.|||||||||||:||||||||||||||||||||||||||||||
Zfish    63 -------------YEEKVQTDRTNRFEYLLKQTEVFAHFIQPAAQKTPTSPLKMKPGRPRIKKDE 114

Human   132 KQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYE 196
            ||||||.||.||||||||||||||:|:||||:|||||:|||||||.|||||||||||||||||||
Zfish   115 KQNLLSAGDNRHRRTEQEEDEELLSENSKATSVCTRFDDSPSYVKTGKLRDYQVRGLNWLISLYE 179

Human   197 NGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLI 261
            |||||||||||||||||||||||||||||||||||||||||||||:|||:|||||||:|::||||
Zfish   180 NGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLYNWMNEFKRWVPSLKAVCLI 244

Human   262 GDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVRE 326
            ||:|:|.||:||.|||||||||||||||||.|::|||||||||||||||||||||||||||||||
Zfish   245 GDREERTAFIRDTLLPGEWDVCVTSYEMLIIERAVFKKFNWRYLVIDEAHRIKNEKSKLSEIVRE 309

Human   327 FKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPF 391
            ||||||||||||||||||||||:||||||||||||::|||:||||||||||.|||||||.|||||
Zfish   310 FKTTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSSEDFDAWFDTNNCLGDTKLVERLHTVLRPF 374

Human   392 LLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLLNILMQLRKC 456
            |||||||||||||.||||:|||||||||||||||:||||||||||||||||||||||:|||||||
Zfish   375 LLRRIKADVEKSLLPKKEIKIYVGLSKMQREWYTKILMKDIDILNSAGKMDKMRLLNVLMQLRKC 439

Human   457 CNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMW 521
            |||||||||||||||||||:|||.|||||||||||||||||||||||||||||||||||||||||
Zfish   440 CNHPYLFDGAEPGPPYTTDLHLVVNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMW 504

Human   522 RNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVD 586
            |||.||||||||||:|||.||||:|||||:||:|||||||||||||||||||||:||||||||||
Zfish   505 RNYGYCRLDGQTPHEERQISINAFNEPNSSKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQVD 569

Human   587 LQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEML 651
            ||||||||||||.|.||||||||||||||||||||||||||||||||||||||.::||:||||||
Zfish   570 LQAMDRAHRIGQKKQVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDPSMNKLGKDEML 634

Human   652 QMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVYNFEG 716
            .:||||||||||||||||||||||||||||.:||.||.||::.:||.||||||||||:|||||||
Zfish   635 SIIRHGATHVFASKESEITDEDIDGILERGERKTMEMKEKMANLGEGSLRNFTMDTENSVYNFEG 699

Human   717 EDYREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRL 781
            ||||||:|:. |.||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   700 EDYREKKKVV-TNWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRL 763

Human   782 FELLEKEILFYRKTIGYKVPRNPELPNAAQAQKEEQLKIDEAESLNDEELEEKEKLLTQGFTNWN 846
            |||||||||:|||||||||||||:|||:|:.|||||.||||||.||:|||||||.||:||||.|.
Zfish   764 FELLEKEILYYRKTIGYKVPRNPDLPNSAEMQKEEQAKIDEAEPLNEEELEEKENLLSQGFTIWT 828

Human   847 KRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARI 911
            ||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||
Zfish   829 KRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARI 893

Human   912 QRRISIKKALDTKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQC 976
            |||||||||||:||||||||||||||||||||||||||||||||||||||||||||:||||||||
Zfish   894 QRRISIKKALDSKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKESVYDELRQC 958

Human   977 IRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPST-QKRKMDGA 1040
            |||||||||||||||||||||||||||||||||||||||||:||||||||||:.|: ||||.||.
Zfish   959 IRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEREKAEKKKRGPRTSSAQKRKQDGT 1023

Human  1041 PDGRGRKKKLKL 1052
            ||||||||||||
Zfish  1024 PDGRGRKKKLKL 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMARCA5	NP_003592.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..83		15/80 (19%)
		PLN03142	69..1012	CDD:215601	851/942 (90%)
		DEAH box	308..311		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1015..1052		30/37 (81%)
smarca5	NP_001075098.2	PLN03142	4..1030	CDD:215601	893/1045 (85%)