Protein Alignment KIF2B and Kif2b

DIOPT Version :9

• Sequence 1: NP_115948.4
• Gene: KIF2B / 84643
• HGNCID: 29443
• Length: 673
• Species: Homo sapiens
• Sequence 2: NP_001005874.2
• Gene: Kif2b / 287624
• RGDID: 1359248
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 673
• Identity: 524/673 - (77%)
• Similarity: 577/673 - (85%)
• Gaps: 9/673 - (1%)

Human     1 MASQFCLPESPCLSPLKPLKPHFGDIQEGIYVAIQRSDKRIHLAVVTEINRENYWVTVEWVEKAV 65
            ||||||||.:|.||||||||.||.|.|.||.||||||||||||||||||||||.|||||||||.|
  Rat     1 MASQFCLPLAPRLSPLKPLKSHFTDFQVGICVAIQRSDKRIHLAVVTEINRENSWVTVEWVEKGV 65

Human    66 KKGKKIDLETILLLNPALDSAEHPMPPPPLSPLALAPSSAIRDQRTATKWVAMIPQKNQTASGDS 130
            ||||||:|||:|||||||.|.||.....||.|:::.|::||.||||||||:||||.:|:|.||||
  Rat    66 KKGKKIELETVLLLNPALASTEHQRSRRPLRPVSVIPATAIGDQRTATKWIAMIPHRNETPSGDS 130

Human   131 LDVRVPSKPCLMKQKKSPCLWEIQKLQEQREKRRRLQQEIRARRALDVNTRNPNYEIMHMIEEYR 195
            ..:.:||.|||||:||||||.||:|||:|||||||||.|||||||||:||.|||:|.|.||||||
  Rat   131 QTLVIPSNPCLMKRKKSPCLREIEKLQKQREKRRRLQLEIRARRALDINTGNPNFETMRMIEEYR 195

Human   196 RHLDSSKISVLEPPQEHRICVCVRKRPLNQRETTLKDLDIITVPSDNVVMVHESKQKVDLTRYLQ 260
            |||||||:|.||||::|||||||||||||:||||:|||||||:||.||||||||||||||||||:
  Rat   196 RHLDSSKMSRLEPPEDHRICVCVRKRPLNERETTMKDLDIITIPSHNVVMVHESKQKVDLTRYLE 260

Human   261 NQTFCFDHAFDDKASNELVYQFTAQPLVESIFRKGMATCFAYGQTGSGKTYTMGGDFSGTAQDCS 325
            ||||||||||||.|||||||||||:|||||||||||||||||||||||||:||||.|||.||:||
  Rat   261 NQTFCFDHAFDDTASNELVYQFTARPLVESIFRKGMATCFAYGQTGSGKTHTMGGAFSGKAQECS 325

Human   326 KGIYALVAQDVFLLLRNSTYEKLDLKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGNQQIQVVGLQ 390
            ||||||||||||||||...||||:|||||||||||||||||||||||||||||||||||||||||
  Rat   326 KGIYALVAQDVFLLLRTPAYEKLELKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGNQQIQVVGLQ 390

Human   391 EKEVCCVEEVLNLVEIGNSCRTSRQTPVNAHSSRSHAVFQIILKSGRIMHGKFSLVDLAGNERGA 455
            |:||.||||||||||:|||||||.||.|||||||||||||:|||.|..:||||||||||||||||
  Rat   391 EQEVGCVEEVLNLVELGNSCRTSGQTSVNAHSSRSHAVFQLILKCGGKLHGKFSLVDLAGNERGA 455

Human   456 DTTKASRKRQLEGAEINKSLLALKECILALGQNKPHTPFRASKLTLVLRDSFIGQNSSTCMIATI 520
            ||.||:|||||||||||||||||||||.|||:||.||||||||||.|||||||||||.|||||||
  Rat   456 DTAKATRKRQLEGAEINKSLLALKECIRALGKNKSHTPFRASKLTQVLRDSFIGQNSYTCMIATI 520

Human   521 SPGMTSCENTLNTLRYANRVKKLNVDVRPYHRGHYPIGHEAPRMLKSHIGNSEMSLQRDEFIKIP 585
            |||||||||||||||||||||:|.::.|||.    |..||.|..|::...|||.|||:|:.|:||
  Rat   521 SPGMTSCENTLNTLRYANRVKELALEARPYP----PTDHEMPLTLENGNTNSEKSLQKDDIIQIP 581

Human   586 YVQSEEQKEIEEVETLPTLLGKDTTISGKGSSQWLENIQERAGGVHHDIDFCIARSLSILEQKID 650
            .||.||:||.:|:.:.     |:...|...|..|.|.|||.|.||:.|:|||||:|||||||||.
  Rat   582 TVQKEEEKESDELTST-----KEPAASWSRSGPWWEAIQETAEGVNCDVDFCIAQSLSILEQKIG 641

Human   651 ALTEIQKKLKLLLADLHVKSKVE 673
            .||||||||:||..||..||:.|
  Rat   642 VLTEIQKKLQLLRDDLQKKSQAE 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIF2B	NP_115948.4	KISc_KIF2_like	213..541	CDD:276818	295/327 (90%)
		Kinesin	219..541	CDD:278646	289/321 (90%)
Kif2b	NP_001005874.2	KISc_KIF2_like	213..541	CDD:276818	295/327 (90%)
		Kinesin	219..542	CDD:278646	290/322 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	583..607		9/28 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83692629
Domainoid	1	1.000	583	1.000	Domainoid score	I5129
eggNOG	1	0.900	-	-		E2759_KOG0246
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23775
Inparanoid	1	1.050	1025	1.000	Inparanoid score	I5256
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG45607
OrthoDB	1	1.010	-	-		D108002at7742
OrthoFinder	1	1.000	-	-		FOG0001531
OrthoInspector	1	1.000	-	-		oto128985
orthoMCL	1	0.900	-	-		OOG6_100492
Panther	1	1.100	-	-	LDO	PTHR24115
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X866
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	18.270