Protein Alignment KIRREL3 and kirrel3

DIOPT Version :10

• Sequence 1: NP_001428181.1
• Gene: KIRREL3 / 84623
• HGNCID: 23204
• Length: 814
• Species: Homo sapiens
• Sequence 2: XP_031761736.1
• Gene: kirrel3 / 105947809
• XenbaseID: XB-GENE-922296
• Length: 773
• Species: Xenopus tropicalis
• Alignment Length: 813
• Identity: 658/813 - (80%)
• Similarity: 720/813 - (88%)
• Gaps: 45/813 - (5%)

Human     2 KPFQLDLLFVCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEARNSHCFLQFGDKAAKGPACSA 66
            ||.:||||.:...|.|:|.|       |.||:|:|||||:|:|.::
 Frog     6 KPSRLDLLLLTCILLSRESG-------LTLGFMSKDKFRKMSEGQS------------------- 44

Human    67 PRPPAPTPEASTFSGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSS 131
                              ||:|||||||||:||||:||||||.|.|.:||||||||:|||||||.
 Frog    45 ------------------SFTQQPQDQVVVAGQPVSLLCAIPGYHGLLLWIKDGLAIGVGRDLSG 91

Human   132 YPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISL 196
            ||:|.|.|:||||||||.|.||||||||:||||||||||||||||||||||||||||.||||||:
 Frog    92 YPRYSVGGDHLSGEHHLMIQRAELQDDAMYECQAIQAAIRSRPARLTVLVPPDDPVITGGPVISI 156

Human   197 RAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSI 261
            |||||||||||||||||||:|.|::.|||:|||||.||||||||||||:||||:|..|:||||:|
 Frog   157 RAGDPLNLTCHADNAKPAATITWMKNGEVLNGATYYKTLLRDGKRESIISTLFVSSSDIENGQTI 221

Human   262 VCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQI 326
            .|||||||:|||||.:|||:|||||||||:||||||||||||.|||:||||||||||||||.|||
 Frog   222 TCRATNKAVPGGKEATVTINIQHPPLVNLTVEPQPVLEDNVVKFHCAAKANPAVTQYRWAKGGQI 286

Human   327 IKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFS 391
            :||.:.|.|.|.||:::|:|||||||||||||||:||||||||||||::||:|:.|||||||.|.
 Frog   287 LKEVTDETYETVVDFSFFTEPVSCEVTNALGSTNVSRTVDVYFGPRMSSEPESITVDLGSDATFH 351

Human   392 CAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPP 456
            |||.|||||||||||||||||||||.|||||:|||||||||||||||||||||||:::|||||||
 Frog   352 CAWIGNPSLTIVWMKRGSGVVLSNENTLTLKNVRQEDAGKYVCRAVVPRVGAGERDISLTVNGPP 416

Human   457 IISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTI 521
            ||||||||||||||||||||||||||||||||||||||||||||||||||||:||:|||||||||
 Frog   417 IISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVSTDEGVISTLTI 481

Human   522 SNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLV 586
            |||||||||||||||||||||||||||||||||..|:||..:|.||||:.|||||||||||||||
 Frog   482 SNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGPNMQSGTSMEPESVPVTVIIGVAVGAGVAFLV 546

Human   587 LMATIVAFCCARSQRNLKGVVSAKNDIRVEIVHKEPASGREGEEHSTIKQLMMDRGEFQQDSVLK 651
            ||||||||||||:|||||||||||||||||||||||::|||.|:||||||||:||||||||||||
 Frog   547 LMATIVAFCCARNQRNLKGVVSAKNDIRVEIVHKEPSTGRETEDHSTIKQLMIDRGEFQQDSVLK 611

Human   652 QLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLRPAGKQRVPTGMSFTNIYS 716
            |||||||||||||||||||||||||||||: |||||||||:||.|||||.|||||||||||||||
 Frog   612 QLEVLKEEEKEFQNLKDPTNGYYSVNTFKD-HSTPTISLSNCQQDLRPANKQRVPTGMSFTNIYS 675

Human   717 TLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDK 781
            |||||.|||||.|||||||||||||||||||||||:|||||||||||||||||||||||||||||
 Frog   676 TLSGQNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSSGKQDGYVQFDK 740

Human   782 ASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV 814
            :|||||||||:|||||||||||:||||||||||
 Frog   741 SSKASASSSHYSQSSSQNSDPSKPLQRRMQTHV 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIRREL3	NP_001428181.1	None
kirrel3	XP_031761736.1	IG_like	50..139	CDD:214653	73/88 (83%)
		Ig strand B	61..65	CDD:409389	2/3 (67%)
		Ig strand C	73..77	CDD:409389	1/3 (33%)
		Ig strand E	100..110	CDD:409389	8/9 (89%)
		Ig strand F	120..125	CDD:409389	3/4 (75%)
		Ig strand G	132..135	CDD:409389	2/2 (100%)
		IgI_2_KIRREL3-like	145..242	CDD:409416	77/96 (80%)
		Ig strand A	146..149	CDD:409416	2/2 (100%)
		Ig strand A'	152..156	CDD:409416	3/3 (100%)
		Ig strand B	163..170	CDD:409416	6/6 (100%)
		Ig strand C	175..180	CDD:409416	2/4 (50%)
		Ig strand C'	183..185	CDD:409416	1/1 (100%)
		Ig strand D	188..195	CDD:409416	5/6 (83%)
		Ig strand E	202..210	CDD:409416	6/7 (86%)
		Ig strand F	219..227	CDD:409416	5/7 (71%)
		Ig strand G	233..239	CDD:409416	3/5 (60%)
		Ig	331..412	CDD:472250	67/80 (84%)
		Ig strand B	348..352	CDD:409549	2/3 (67%)
		Ig strand C	361..365	CDD:409549	3/3 (100%)
		Ig strand E	377..381	CDD:409549	2/3 (67%)
		IgI_5_KIRREL3	414..511	CDD:409479	94/96 (98%)
		Ig strand A	415..419	CDD:409479	3/3 (100%)
		Ig strand A'	421..424	CDD:409479	2/2 (100%)
		Ig strand B	432..439	CDD:409479	6/6 (100%)
		Ig strand C	446..451	CDD:409479	4/4 (100%)
		Ig strand C'	453..456	CDD:409479	2/2 (100%)
		Ig strand D	464..471	CDD:409479	5/6 (83%)
		Ig strand E	474..481	CDD:409479	6/6 (100%)
		Ig strand F	492..499	CDD:409479	6/6 (100%)
		Ig strand G	502..509	CDD:409479	6/6 (100%)