Protein Alignment TPST1 and Tpst

DIOPT Version :9

• Sequence 1: XP_005250699.1
• Gene: TPST1 / 8460
• HGNCID: 12020
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_001259518.1
• Gene: Tpst / 32312
• FlyBaseID: FBgn0086674
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 206/336 - (61%)
• Similarity: 260/336 - (77%)
• Gaps: 3/336 - (0%)

Human    14 LVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVP 78
            :::.::.:|...:....|..:::..::   |.|....|...|.....:.::|:::||||||||||
  Fly    18 IIVITMFLFKFTELRPTCLFKVDAANE---LSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVP 79

Human    79 RSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLL 143
            ||||||||||||||||:|||:|||||||||.|:..|.:|.||.:||.|||:|.||::||:..|.|
  Fly    80 RSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCL 144

Human   144 EIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSY 208
            |||.|||||||.||||||..||..:|:..||||||||.|||||||:|||:|||||||.||||:||
  Fly   145 EIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSY 209

Human   209 RDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIG 273
            |.|:.|||.|||.|:.||.::|..:||:|:|||||||||.|||.:||||.:|||.:||||||.|.
  Fly   210 RQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFIN 274

Human   274 KAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 338
            |..||.|||||||:||||||||:.|:|||||:||.||::|||.|||||:.||||||||||:||||
  Fly   275 KPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKP 339

Human   339 DPKIIENTRRV 349
            |..:.:||.::
  Fly   340 DAWVQDNTSKL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPST1	XP_005250699.1	Sulfotransfer_3	69..257	CDD:290204	134/187 (72%)
Tpst	NP_001259518.1	Sulfotransfer_3	70..258	CDD:290204	134/187 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144478
Domainoid	1	1.000	300	1.000	Domainoid score	I1422
eggNOG	1	0.900	-	-		E2759_KOG3988
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2667
Inparanoid	1	1.050	434	1.000	Inparanoid score	I1709
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003498
OrthoInspector	1	1.000	-	-		otm41348
orthoMCL	1	0.900	-	-		OOG6_104250
Panther	1	1.100	-	-	O	PTHR12788
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2858
SonicParanoid	1	1.000	-	-		X2392
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.780