Protein Alignment MEGF10 and megf10

DIOPT Version :9

• Sequence 1: XP_016865476.1
• Gene: MEGF10 / 84466
• HGNCID: 29634
• Length: 1195
• Species: Homo sapiens
• Sequence 2: NP_001072726.1
• Gene: megf10 / 780183
• XenbaseID: XB-GENE-491974
• Length: 1114
• Species: Xenopus tropicalis
• Alignment Length: 1128
• Identity: 931/1128 - (82%)
• Similarity: 1016/1128 - (90%)
• Gaps: 16/1128 - (1%)

Human    56 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILN 120
            ||.|| ..|....|:|..|:||.|.|||||||||||||||||||||||.||:||:||||||||||
 Frog     1 MVHSL-KWLGIFPLILFQWLGTTSSLNLEDPNVCSHWESYSVTVQESYSHPYDQVYYTSCTDILN 64

Human   121 WFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGW 185
            ||||||||:|||||||.|||||||||||||||||||.||||||||||||||||||||||||||||
 Frog    65 WFKCTRHRISYRTAYRRGEKTMYRRKSQCCPGFYESREMCVPHCADKCVHGRCIAPNTCQCEPGW 129

Human   186 GGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRC 250
            ||.|||||||.|||||||:||||||||||||||||||||::|::|||||:||:||||||||.|:|
 Frog   130 GGPNCSSACDVDHWGPHCSSRCQCKNGALCNPITGACHCSSGYKGWRCEERCDQGTYGNDCQQKC 194

Human   251 QCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWM 315
            ||||||:|||||||||||||||||||||||||||||.|||:||||||||||||||||||||:|||
 Frog   195 QCQNGASCDHVTGECRCPPGYTGAFCEDLCPPGKHGSQCEERCPCQNGGVCHHVTGECSCPAGWM 259

Human   316 GTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQ 380
            ||||||||||||:|:|||||||||||||||:|||||:|||||.|||||:|||||.|||.||:|||
 Frog   260 GTVCGQPCPEGRYGRNCSQECQCHNGGTCDSATGQCYCSPGYNGERCQEECPVGLYGVKCAQTCQ 324

Human   381 CVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPG 445
            |:|||||||:|||||||.|:.|||||..||.||.||:||||:|||||:.|.||||||||||||||
 Frog   325 CLNGGKCYHISGACLCEPGYTGERCETPLCSEGTYGMKCDKKCPCHLQYTQSCHPMSGECACKPG 389

Human   446 WSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSR 510
            .||||||||||.|||||.||||||||||||||||||||.|||||.|:||||.||.||||:||||.
 Frog   390 RSGLYCNETCSLGFYGEFCQQICSCQNGADCDSVTGKCICAPGFTGVDCSTACPPGTYGVNCSSL 454

Human   511 CGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGW 575
            |.|||:|||||||||||||||||||||||.||.|:||.|||||||||||||||.|||||||||||
 Frog   455 CNCKNNAVCSPVDGSCTCKAGWHGVDCSINCPRGSWGLGCNLTCQCLNGGACNPLDGTCTCAPGW 519

Human   576 RGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPC 640
            ||.||||||||||||:||.|||||||||||||.||:||||.||:|:||||||..|.|||||||.|
 Frog   520 RGLKCELPCQDGTYGMNCIERCDCSHADGCHPATGYCRCLAGWAGMHCDSVCPGGHWGPNCSLSC 584

Human   641 YCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPG 705
            .|||||||||||||||||||:||||||||||||||||||||.|||||||:|||||:||.||||.|
 Frog   585 DCKNGASCSPDDGICECAPGYRGTTCQRICSPGFYGHRCSQACPQCVHSNGPCHHVTGQCDCLAG 649

Human   706 FTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHT 770
            |.|:||||||||||:||||||:|.|||||||||||.:|||||||||:||||.|||.|||||||||
 Frog   650 FMGSLCNEVCPSGRYGKNCAGVCACTNNGTCNPIDGTCQCYPGWIGNDCSQACPPGHWGPNCIHT 714

Human   771 CNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF 835
            |||||||:||||||||||:|||||||||||||||:|||:|.|:||||||||||||:|||||||||
 Frog   715 CNCHNGAYCSAYDGECKCSPGWTGLYCTQRCPLGYYGKECTLVCQCQNGADCDHITGQCTCRTGF 779

Human   836 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRT 900
            ||:.|||||||.:|||||||:||||||||||||||||||||||||||||||.:|:||||||||||
 Frog   780 MGKFCEQKCPSASYGYGCRQVCDCLNNSTCDHITGTCYCSPGWKGARCDQAVMIVVGNLNSLSRT 844

Human   901 STALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMRVVNADYTISG 965
            |.|:|||||||||||||||||||||||||||||||.|||||:::||||.||||:||::.||||:.
 Frog   845 SAAIPADSYQIGAIAGIIILVLVVLFLLALFIIYRQKQKGKDTAMPAVAYTPAVRVLSTDYTIAD 909

Human   966 TLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFVNLKNVNPGKRGPVGD 1030
            ||||:|..||||.||:|||||||:||.|.|.||:.|||.|::||::||||||||::||||....|
 Frog   910 TLPHNNVVNANSQYFSNPSYHTLSQCTTGPQVNSMDRMMVSRSKSSQLFVNLKNLDPGKRSHTID 974

Human  1031 CTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSNCSLSSSENPYATIKDPPVLI 1095
            .|||||||||.||:|||.|               |.|||.|:.|.|||||:|||||||||||||:
 Frog   975 YTGTLPADWKQGGFLNENG---------------LLKNSAYSISTCSLSSTENPYATIKDPPVLL 1024

Human  1096 PKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNS 1160
            ||:.|||||||||||||||.||||:||:.||:||||||||||||||.|.|||::|||.|||||||
 Frog  1025 PKNIECGYVEMKSPARRDSAYAEISNSSLANKNVYEVEPTVSVVQGAFCNNGKISQDLYDLPKNS 1089

Human  1161 HIPCHYDLLPVRDSSSSPKQEDS 1183
            ||||||||||||:||||.|.|.:
 Frog  1090 HIPCHYDLLPVRESSSSNKDEST 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEGF10	XP_016865476.1	None
megf10	NP_001072726.1	EMI	31..98	CDD:369419	61/66 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	435	1.000	Domainoid score	I5069
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23771
Inparanoid	1	1.050	2179	1.000	Inparanoid score	I542
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG47996
OrthoDB	1	1.010	-	-		D21863at32523
OrthoFinder	1	1.000	-	-		FOG0001631
OrthoInspector	1	1.000	-	-		oto151221
Panther	1	1.100	-	-	LDO	PTHR24035
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5768
SonicParanoid	1	1.000	-	-		X1195
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	14.110