DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MEGF10 and NimA

DIOPT Version :9

Sequence 1:XP_016865476.1 Gene:MEGF10 / 84466 HGNCID:29634 Length:1195 Species:Homo sapiens
Sequence 2:NP_001285918.1 Gene:NimA / 318930 FlyBaseID:FBgn0261514 Length:565 Species:Drosophila melanogaster


Alignment Length:228 Identity:75/228 - (32%)
Similarity:104/228 - (45%) Gaps:12/228 - (5%)


- Green bases have known domain annotations that are detailed below.


Human    47 FCRVVLQKKMVISL----NSCLSFICLLLCHWIGTASPLNLEDP-NVCSHWESYSVTVQESYPHP 106
            |.:::|...||:.|    ||.|.....:.....|..:..:::.| |:|...|.|...||.....|
  Fly     7 FGKLLLLLAMVLPLGSGQNSTLKINTNVKDIEAGVVALPSIQGPGNICIREEPYVEHVQVPEMQP 71

Human   107 FDQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGF----YESGEMCVPHCADK 167
            ......:.|.:|..  :|...:...|...|..:....|....||.|:    .:|...|.|.|...
  Fly    72 VRVRTSSWCMEIPP--RCATFKTEMREVMRVQKLNKTRTVRFCCQGYEGNLSDSQATCKPICRGG 134

Human   168 CVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWR 232
            |..|.|:.|:.|.||.|:.|.:|:..||.|.||..|.:.|||:|||.|:..:|.|||.||:.|..
  Fly   135 CGRGSCVMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNLCQCQNGAACDNKSGLCHCIAGWTGQF 199

Human   233 CEDRCEQGTYGNDCHQRCQCQNGATCDHVTGEC 265
            ||..|.|||||..|.:.|.|.. ..|:..||.|
  Fly   200 CELPCPQGTYGIMCRKACDCDE-KPCNPQTGAC 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MEGF10XP_016865476.1 None
NimANP_001285918.1 EMI 52..116 CDD:284877 15/65 (23%)
EGF_2 170..200 CDD:285248 15/29 (52%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D561378at2759
OrthoFinder 1 1.000 - - FOG0001631
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.820

Return to query results.
Submit another query.