DRSC/TRiP Functional Genomics Resources

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Protein Alignment MEGF11 and CG17145

DIOPT Version :9

Sequence 1:NP_001371957.1 Gene:MEGF11 / 84465 HGNCID:29635 Length:1140 Species:Homo sapiens
Sequence 2:NP_001262098.1 Gene:CG17145 / 40215 FlyBaseID:FBgn0036953 Length:334 Species:Drosophila melanogaster


Alignment Length:329 Identity:71/329 - (21%)
Similarity:109/329 - (33%) Gaps:102/329 - (31%)


- Green bases have known domain annotations that are detailed below.


Human   314 CSQHCDCHNG----GQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTI---- 370
            |||...|.:.    ..|:.:|...:.:.|    :|.:.|   ......|::.|...|...:    
  Fly    45 CSQSITCIDSVSYYSTCTGSTPFFDKDTG----KCVKSL---STSTSSCSISCADRAKQFVADPK 102

Human   371 SCHPVTGACTCQPGWSGHHCNE-------SCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGF 428
            ||:          |:  ::|.:       :||...:.:.....|:.|:.:||.:.|         
  Fly   103 SCY----------GY--YYCADEETALYGTCPQETHFNATTQMCSRQHESDCTTST--------- 146

Human   429 MGEVCAVSCAAGTYGPNCSSICSCN----------NGGTCSPV-----DGSCTCKEGWQGLDCTL 478
             .|.|::.    ..|.|..::..||          ...|||..     .|.|..|   ..:||..
  Fly   147 -FEYCSIV----KNGVNFDNLQGCNMYHVCEKGVLKDKTCSKTYYQASTGECVSK---ALVDCDA 203

Human   479 -PCPSGTWGLNCN--------ESCTCANGAACS-PIDGSCSCTPGWLGDTCELPCPDGTFGLNCS 533
             |.|:...|....        :..||.....|: ..||:....|.|      ..||...|....|
  Fly   204 HPLPTDVCGKASKPYENKFVADEATCRGYFYCAKQKDGTPDPNPVW------NQCPQDRFFDASS 262

Human   534 EHC------DCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CSCEN------GG 585
            :.|      .||| |.||..|. ...::...|.|...:|..|     .:|| .||.|      .|
  Fly   263 QMCITPSSVYCSH-DRCDGRTA-SFVVSATKGCRNYLSCSDG-----VTVSERSCGNYFFDDQQG 320

Human   586 SCSP 589
            :|:|
  Fly   321 ACTP 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MEGF11NP_001371957.1 EMI 26..93 CDD:400092
EGF_CA 275..320 CDD:419698 3/5 (60%)
EGF_CA 362..409 CDD:419698 9/57 (16%)
CG17145NP_001262098.1 CBM_14 91..142 CDD:279884 9/62 (15%)
CBM_14 278..327 CDD:279884 15/53 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D561378at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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