DRSC/TRiP Functional Genomics Resources

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Protein Alignment MEGF11 and NimC4

DIOPT Version :9

Sequence 1:NP_001371957.1 Gene:MEGF11 / 84465 HGNCID:29635 Length:1140 Species:Homo sapiens
Sequence 2:NP_609698.2 Gene:NimC4 / 34824 FlyBaseID:FBgn0260011 Length:377 Species:Drosophila melanogaster


Alignment Length:382 Identity:82/382 - (21%)
Similarity:115/382 - (30%) Gaps:154/382 - (40%)


- Green bases have known domain annotations that are detailed below.


Human    10 AFSFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAY 74
            |...:..::|.|.|..|.|...|:...||..:.    .:|...:.:....|.|..:....|.:..
  Fly     6 ALILVLGSIAANAERDNYCERNETIRATVPVTK----QRIIVKQPSKWKIWKKTEKITEIYDSEE 66

Human    75 RRGLRTMYRRRSQCCPGY--YESGDFCIPLCTEEC-VHGRCVSPDTCHCEPGWGGPDCSSGCDSD 136
            .:....:.|   :|||||  .||| .|.|:|:..| .|..|.:||.|.|..|:  ....:..|..
  Fly    67 EQVTHRLVR---ECCPGYLQVESG-LCEPICSRGCPAHASCAAPDRCECISGY--VSARNHQDGS 125

Human   137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASC-DPR 200
            |:               |.||                           |:.||..  ||.| .|.
  Fly   126 HY---------------CEPI---------------------------CETPCPA--GAQCVTPN 146

Human   201 AGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPG 265
            .  |.|..|||.:.                  |..:|     ::|.||       .||       
  Fly   147 T--CACRDGYTQLQ------------------PTDDG-----VSGGCA-------PVC------- 172

Human   266 TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEEC------------------------- 305
            ..|..|:       .|:|..| .:|.|.:||..|:.:|.|                         
  Fly   173 RVGDGCA-------NGKCIDV-DRCACNSGYRWDKAEERCIELSAESISEELETTEDNTDSPSTS 229

Human   306 ------------PFGSFGFQC------SQHCDCHNGGQCSP-----TTGACECEPGY 339
                        .|..|..:|      |....|...| |.|     .:|.|:|..||
  Fly   230 STAVFTATHCPDDFVLFRGECREKQFDSNDVGCLKSG-CGPHQTCLDSGVCQCSDGY 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MEGF11NP_001371957.1 EMI 26..93 CDD:400092 15/68 (22%)
EGF_CA 275..320 CDD:419698 14/87 (16%)
EGF_CA 362..409 CDD:419698
NimC4NP_609698.2 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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