DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MEGF11 and NimA

DIOPT Version :9

Sequence 1:	NP_001371957.1	Gene:	MEGF11 / 84465	HGNCID:	29635	Length:	1140	Species:	Homo sapiens
Sequence 2:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	71/207 - (34%)
Similarity:	96/207 - (46%)	Gaps:	22/207 - (10%)

- Green bases have known domain annotations that are detailed below.

Human     7 GLIAFSFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFKCTRHRISYK 71
            |::|...:|.       ..|:|...|.|...||.....|......:.|.:|..  :|.    ::|
  Fly    40 GVVALPSIQG-------PGNICIREEPYVEHVQVPEMQPVRVRTSSWCMEIPP--RCA----TFK 91

Human    72 TAYRRGLRTMYRRRSQ----CCPGY----YESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPD 128
            |..|..:|.....:::    ||.||    .:|...|.|:|...|..|.||.||.|.||.|:.|..
  Fly    92 TEMREVMRVQKLNKTRTVRFCCQGYEGNLSDSQATCKPICRGGCGRGSCVMPDICSCEEGYIGKH 156

Human   129 CSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRH 193
            |:..||.|.||..|.|.|||||||.|:..:|.|.|.||:.|..||..|..||:|..|:..|.|..
  Fly   157 CTQRCDHDRWGLDCKNLCQCQNGAACDNKSGLCHCIAGWTGQFCELPCPQGTYGIMCRKACDCDE 221

Human   194 GASCDPRAGECL 205
             ..|:|:.|.|:
  Fly   222 -KPCNPQTGACI 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MEGF11	NP_001371957.1	EMI	26..93	CDD:400092	18/74 (24%)
		EGF_CA	275..320	CDD:419698
		EGF_CA	362..409	CDD:419698
NimA	NP_001285918.1	EMI	52..116	CDD:284877	16/69 (23%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	16/29 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	1	1.000	-	-		FOG0001631
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820