Protein Alignment MEGF11 and NimB2

DIOPT Version :9

• Sequence 1: NP_001371957.1
• Gene: MEGF11 / 84465
• HGNCID: 29635
• Length: 1140
• Species: Homo sapiens
• Sequence 2: NP_723857.1
• Gene: NimB2 / 260645
• FlyBaseID: FBgn0028543
• Length: 421
• Species: Drosophila melanogaster
• Alignment Length: 364
• Identity: 94/364 - (25%)
• Similarity: 120/364 - (32%)
• Gaps: 139/364 - (38%)

Human    88 CCPGYYESGDF---CIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPH-------C 142
            ||.||..:...   |.|:|.::|.:|.|.:|:||.|.||                 |       |
  Fly   167 CCDGYERNPHIYRRCEPICADDCRNGICTAPNTCVCIPG-----------------HVRTAEGKC 214

Human   143 SNRCQ--CQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECL 205
            .:.|.  |.||.                   |:|           :..|:||.|.|.:|.
  Fly   215 ISTCPLGCGNGV-------------------CDE-----------RNECKCREGYSLEPE----- 244

Human   206 CAPGYTGVYCEELCPPGSHGAHCEL-RCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQ 269
                 |..||:..|.||     |.. ||...|         :|||..|:..|.          ..
  Fly   245 -----TRKYCQPECKPG-----CSFGRCVAPN---------KCACLDGYRLAA----------DG 280

Human   270 NCSQDCPCHHGGQCDHVTGQCHCTAGY--MGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA 332
            :|...|.....|:|. ..|.|:|.|||  :..||:..|..           .|.||....|  ..
  Fly   281 SCEPVCDSCENGKCT-APGHCNCNAGYLKLQGRCEPICSI-----------PCKNGRCIGP--DI 331

Human   333 CECEPGYKGPRCQERLCPEGLHGPGCTLPC---PCDADNTISCHPVTGAC-------TCQPGWSG 387
            |||..|::..|......|:      |.|||   .|..:|...|.  ||..       .|||
  Fly   332 CECASGFEWDRKSAECLPK------CDLPCLNGVCVGNNQCDCK--TGYVRDEHQRNICQP---- 384

Human   388 HHCNESCPVGYYGDGCQLP--CTCQNGADCHSITGGCTC 424
             ||.:.|..||    |..|  |.|:.|.....|.|..||
  Fly   385 -HCPQGCQNGY----CSAPNFCICRPGFIKSGIKGRQTC 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEGF11	NP_001371957.1	EMI	26..93	CDD:400092	3/4 (75%)
		EGF_CA	275..320	CDD:419698	12/46 (26%)
		EGF_CA	362..409	CDD:419698	17/58 (29%)
NimB2	NP_723857.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810