Protein Alignment ZNF333 and scrt1b

DIOPT Version :9

• Sequence 1: NP_115809.1
• Gene: ZNF333 / 84449
• HGNCID: 15624
• Length: 665
• Species: Homo sapiens
• Sequence 2: NP_001014369.1
• Gene: scrt1b / 541533
• ZFINID: ZDB-GENE-050327-72
• Length: 279
• Species: Danio rerio
• Alignment Length: 296
• Identity: 85/296 - (28%)
• Similarity: 134/296 - (45%)
• Gaps: 62/296 - (20%)

Human   265 DRGVLSDTCAEPQCQPQEAIPSQDTFTEILSIDVKGEQPQPGEKLYKYNELE--KPFNSIEPLFQ 327
            |:|.:||... |.....|:    |..|::         |.|| .:|..|..:  .| :|.:|...
Zfish    37 DKGYISDYIT-PAIYDGES----DGGTKV---------PSPG-PIYDSNHSDYGAP-DSDQPDSP 85

Human   328 YQRIHAGEASCECQEIRNSFFQSAHLIVP----EKIRSGDKSYACNKCEKSFRYSSDLIRHEKTH 388
            ...|.:|..:.: ..:...:...|..|..    .|:.||.::               |.||
Zfish    86 QSEITSGYINGD-NAVSEGYTVDAFFITDGRSRRKVISGSRT---------------LQRH---- 130

Human   389 TAEKCFDCQECGQAFKYSSNLRRHMRTH---TGEKPFECSQCGKTFTRNFNLILHQRNHTGEKPY 450
                  .|.|||:.:..||||.||.:||   ..:...:|..|||.:.....:.:|...|  :..:
Zfish   131 ------TCNECGKTYATSSNLSRHKQTHRSLDSKMAKKCPTCGKVYVSMPAMAMHLLTH--DLKH 187

Human   451 ECKDCGKAFNQPSSLRSHVRTHTGEKPFECSQCGKAFREHSSLKTHLRTHTREKPYECNQCGKPF 515
            :|..|||||::|..|:.|:|:|||||||.|:.|||||.:.|:|:.|::||:..|.::|.:|.|.|
Zfish   188 KCDICGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFKCKRCNKTF 252

Human   516 RTSTHLNVHKRIHTGEKLYECATCGQVLSRLSTLKS 551
            ...::||.|         ||.|......|..|::::
Zfish   253 VLKSYLNKH---------YESACFKGAFSPHSSIEA 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF333	NP_115809.1	KRAB	4..61	CDD:214630
		KRAB	4..41	CDD:279668
		KRAB	203..263	CDD:214630
		KRAB	203..242	CDD:279668
		COG5048	<228..525	CDD:227381	79/268 (29%)
		C2H2 Zn finger	340..360	CDD:275368	3/23 (13%)
		zf-C2H2	366..388	CDD:278523	3/21 (14%)
		C2H2 Zn finger	368..388	CDD:275368	3/19 (16%)
		zf-C2H2	394..416	CDD:278523	10/21 (48%)
		C2H2 Zn finger	396..416	CDD:275368	10/19 (53%)
		zf-H2C2_2	408..433	CDD:290200	10/27 (37%)
		C2H2 Zn finger	424..444	CDD:275368	5/19 (26%)
		zf-H2C2_2	436..461	CDD:290200	8/24 (33%)
		C2H2 Zn finger	452..472	CDD:275368	10/19 (53%)
		zf-H2C2_2	464..487	CDD:290200	14/22 (64%)
		C2H2 Zn finger	480..500	CDD:275368	9/19 (47%)
		zf-H2C2_2	492..517	CDD:290200	9/24 (38%)
		C2H2 Zn finger	508..528	CDD:275368	7/19 (37%)
		zf-H2C2_2	520..545	CDD:290200	6/24 (25%)
		C2H2 Zn finger	536..556	CDD:275368	3/16 (19%)
		zf-H2C2_2	549..572	CDD:290200	0/3 (0%)
		C2H2 Zn finger	564..584	CDD:275368
		zf-H2C2_2	576..599	CDD:290200
		zf-C2H2	590..612	CDD:278523
		C2H2 Zn finger	592..612	CDD:275368
		zf-C2H2	618..640	CDD:278523
		C2H2 Zn finger	620..640	CDD:275368
scrt1b	NP_001014369.1	zf-C2H2	130..152	CDD:278523	11/31 (35%)
		C2H2 Zn finger	132..152	CDD:275368	10/19 (53%)
		C2H2 Zn finger	163..180	CDD:275371	4/16 (25%)
		COG5048	187..>263	CDD:227381	36/84 (43%)
		zf-C2H2	187..209	CDD:278523	10/21 (48%)
		C2H2 Zn finger	189..209	CDD:275368	10/19 (53%)
		C2H2 Zn finger	217..237	CDD:275368	9/19 (47%)
		zf-C2H2	217..237	CDD:278523	9/19 (47%)
		zf-H2C2_2	229..253	CDD:290200	8/23 (35%)
		C2H2 Zn finger	245..261	CDD:275368	6/15 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910