DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ABLIM2 and Pax

DIOPT Version :9

Sequence 1:	XP_005248071.1	Gene:	ABLIM2 / 84448	HGNCID:	19195	Length:	701	Species:	Homo sapiens
Sequence 2:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	74/221 - (33%)
Similarity:	100/221 - (45%)	Gaps:	16/221 - (7%)

- Green bases have known domain annotations that are detailed below.

Human    29 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQ 93
            ||.|.....|:|:....|.:|.:.|.|..|..:|....||.|.|...|..||..|:..||..|:.
  Fly   348 CNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNG 412

Human    94 FIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSC 158
            .|..:.|:||.||:|.:.|.||.|...|         |:|...::...|..  .:.:.......|
  Fly   413 AILDKCVTALDKTWHTEHFFCAQCGQQF---------GEEGFHERDGKPYC--RNDYFEMFAPKC 466

Human   159 GGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCEADYHAKFGIRCDSCEK 222
            .||...|.... :.||:..||..||.|:.|.: .....:...:||||||..||||.|..|..|.|
  Fly   467 NGCNRAIMENY-ISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSK 530

Human   223 YITGRVLEAGEKHYHPS---CALCVR 245
            .||||.:.|..|.:||.   ||.|::
  Fly   531 PITGRCITAMFKKFHPEHFVCAFCLK 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ABLIM2	XP_005248071.1	LIM1_abLIM	29..80	CDD:188713	16/50 (32%)
		LIM2_abLIM	85..140	CDD:188714	17/54 (31%)
		LIM3_abLIM	158..209	CDD:188715	18/51 (35%)
		LIM4_abLIM	217..272	CDD:188716	14/32 (44%)
		AbLIM_anchor	282..665	CDD:292800
		VHP	667..701	CDD:280388
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	17/51 (33%)
		LIM2_Paxillin_like	407..458	CDD:188723	17/61 (28%)
		LIM3_Paxillin_like	466..518	CDD:188724	18/52 (35%)
		LIM4_Paxillin	525..576	CDD:188795	14/32 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910