DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ABLIM2 and jub

DIOPT Version :9

Sequence 1:	XP_005248071.1	Gene:	ABLIM2 / 84448	HGNCID:	19195	Length:	701	Species:	Homo sapiens
Sequence 2:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	58/250 - (23%)
Similarity:	80/250 - (32%)	Gaps:	106/250 - (42%)

- Green bases have known domain annotations that are detailed below.

Human    28 LCNTCGNVCK--GEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY------ 84
            :|:|||...|  |:..:.....:|..||:|.:||..|....|:...|...|..||  :|
  Fly   515 ICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDY--MYSGFQQT 577

Human    85 GTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSA 149
            ..:|..|...|...::.|:||:|||.||.|.||              .||:
  Fly   578 AEKCAICGHLIMEMILQAMGKSYHPGCFRCCVC--------------NECL-------------- 614

Human   150 HLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLP---------YC 205
                                                              ||:|         ||
  Fly   615 --------------------------------------------------DGVPFTVDVDHKIYC 629

Human   206 EADYHAKFGIRCDSCEKYITG--------RVLEAGEKHYHPSCALCVRCGQMFAE 252
            ..|||..|..:|.||.|.||.        ||:.. :|.:|..|.:|..||....:
  Fly   630 VNDYHRMFAPKCASCGKGITPVEGTDETVRVVSM-DKDFHVDCYICEECGMQLTD 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ABLIM2	XP_005248071.1	LIM1_abLIM	29..80	CDD:188713	16/52 (31%)
		LIM2_abLIM	85..140	CDD:188714	16/54 (30%)
		LIM3_abLIM	158..209	CDD:188715	5/59 (8%)
		LIM4_abLIM	217..272	CDD:188716	14/43 (33%)
		AbLIM_anchor	282..665	CDD:292800
		VHP	667..701	CDD:280388
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	16/52 (31%)
		LIM2_Ajuba_like	581..633	CDD:188741	21/129 (16%)
		LIM3_Ajuba_like	641..702	CDD:188822	14/43 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910