Protein Alignment PCGF5 and l(3)73Ah

DIOPT Version :10

• Sequence 1: NP_115749.2
• Gene: PCGF5 / 84333
• HGNCID: 28264
• Length: 256
• Species: Homo sapiens
• Sequence 2: NP_524933.1
• Gene: l(3)73Ah / 48903
• FlyBaseID: FBgn0002283
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 101/259 - (38%)
• Similarity: 155/259 - (59%)
• Gaps: 47/259 - (18%)

Human     4 QRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
            :|:..:|..||:|||.||.||.|..||||||||||||:|:|:|.|:...||.|.|.:|:::||:.
  Fly     2 ERRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQY 66

Human    69 LRLDNTLEEIIFKLVPGLREQELERESEFWK-KNKP-----QENGQDDTSKADKPKVDEEGDENE 127
            :..|.|:::|::||||.|:|.|..||.:|:| :|.|     .:|.:||..|.    :|...
  Fly    67 ISFDRTMQDIVYKLVPKLQEDESRRERDFYKSRNMPCPKDITQNHEDDNEKV----MDAHA---- 123

Human   128 DDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKL--KLPSSY 190
             :.|:||.|.|:.:||:|:.||       .|.|.::|||||::.|:..:||.::.|:  .:....
  Fly   124 -ESDFHRLDEQVNVCLECISNN-------FKNLQRRFIRCSSQATITHLKKLVAKKILNGIEKYR 180

Human   191 ELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVLQYRPRID 254
            |:|:|||.|::|||||::|:|:||||.|..                       |:.||:|||::
  Fly   181 EIDILCNEELLGKDHTLKFVYVTRWRFRDP-----------------------PLRLQFRPRVE 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PCGF5	NP_115749.2	RING-HC_PCGF5	6..100	CDD:438395	48/94 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..133		11/44 (25%)
		RAWUL_PCGF5	136..256	CDD:340604	42/121 (35%)
l(3)73Ah	NP_524933.1	RING_Ubox	4..96	CDD:473075	46/91 (51%)
		RAWUL_PCGF3	133..217	CDD:340603	38/113 (34%)