Protein Alignment VPS25 and VPS25

DIOPT Version :10

• Sequence 1: NP_115729.1
• Gene: VPS25 / 84313
• HGNCID: 28122
• Length: 176
• Species: Homo sapiens
• Sequence 2: NP_012636.1
• Gene: VPS25 / 853566
• SGDID: S000003863
• Length: 202
• Species: Saccharomyces cerevisiae
• Alignment Length: 185
• Identity: 58/185 - (31%)
• Similarity: 93/185 - (50%)
• Gaps: 27/185 - (14%)

Human     8 PWQYRFPPFFTLQPNVDTRQKQLAAWCSLVLSFCRLHKQSSM----TVMEAQE------------ 56
            |..|.|||.:|.|||..||::|::.|..::..:|:..|...|    ||:...|
Yeast     5 PPVYSFPPLYTRQPNSLTRRQQISTWIDIISQYCKTKKIWYMSVDGTVINDNELDSGSTDNDDSK 69

Human    57 ---SPLFNNVKLQRKLPVESIQIVLEELRKKGNLEWLDKS--KSS------FLIMWRRPEEWGKL 110
               ..||||..:||.:....|..:..::.|:|....:|:|  :||      :.|:|:..:.|..|
Yeast    70 KISKNLFNNEDIQRSVSQVFIDEIWSQMTKEGKCLPIDQSGRRSSNTTTTRYFILWKSLDSWASL 134

Human   111 IYQWVSRSGQNNSVFTLYELTNGEDTEDEEFHGLDEATLLRALQALQQEHKAEII 165
            |.||...||:.|.|.|||||:.|::|.:.|||.:.|:.|...|:.|...::|.::
Yeast   135 ILQWFEDSGKLNQVITLYELSEGDETVNWEFHRMPESLLYYCLKPLCDRNRATML 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VPS25	NP_115729.1	ESCRT-II	10..139	CDD:461763	49/155 (32%)
VPS25	NP_012636.1	ESCRT-II	7..163	CDD:461763	57/183 (31%)