Protein Alignment VPS25 and vps25

DIOPT Version :9

• Sequence 1: NP_115729.1
• Gene: VPS25 / 84313
• HGNCID: 28122
• Length: 176
• Species: Homo sapiens
• Sequence 2: NP_001082831.2
• Gene: vps25 / 407684
• ZFINID: ZDB-GENE-050506-30
• Length: 174
• Species: Danio rerio
• Alignment Length: 174
• Identity: 136/174 - (78%)
• Similarity: 154/174 - (88%)
• Gaps: 0/174 - (0%)

Human     3 MSFEWPWQYRFPPFFTLQPNVDTRQKQLAAWCSLVLSFCRLHKQSSMTVMEAQESPLFNNVKLQR 67
            |||||||||.|||||||||||||||||||||||||||:||..|..::.|:||||||:|||.|::|
Zfish     1 MSFEWPWQYNFPPFFTLQPNVDTRQKQLAAWCSLVLSYCRHRKLYTLDVLEAQESPVFNNKKIER 65

Human    68 KLPVESIQIVLEELRKKGNLEWLDKSKSSFLIMWRRPEEWGKLIYQWVSRSGQNNSVFTLYELTN 132
            ||.||:||:|.||||||||||||||:||..|||||||||||||||||||::|..|||||||||.|
Zfish    66 KLSVEAIQVVFEELRKKGNLEWLDKNKSRCLIMWRRPEEWGKLIYQWVSKNGMVNSVFTLYELAN 130

Human   133 GEDTEDEEFHGLDEATLLRALQALQQEHKAEIITVSDGRGVKFF 176
            |:|||.||||||::..|||:|||||.:.|||||||.||:|||||
Zfish   131 GDDTEKEEFHGLEDWMLLRSLQALQTDGKAEIITVDDGKGVKFF 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VPS25	NP_115729.1	ESCRT-II	10..139	CDD:399106	101/128 (79%)
vps25	NP_001082831.2	ESCRT-II	8..143	CDD:283517	106/134 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194332155
Domainoid	1	1.000	231	1.000	Domainoid score	I10699
eggNOG	1	0.900	-	-		E1_KOG4068
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6303
Inparanoid	1	1.050	289	1.000	Inparanoid score	I9697
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54593
OrthoDB	1	1.010	-	-		D1094121at2759
OrthoFinder	1	1.000	-	-		FOG0004660
OrthoInspector	1	1.000	-	-		oto48683
orthoMCL	1	0.900	-	-		OOG6_103180
Panther	1	1.100	-	-	LDO	PTHR13149
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1645
SonicParanoid	1	1.000	-	-		X3846
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	18	18.340