Protein Alignment CHCHD6 and Chchd3

DIOPT Version :10

• Sequence 1: NP_001307539.1
• Gene: CHCHD6 / 84303
• HGNCID: 28184
• Length: 236
• Species: Homo sapiens
• Sequence 2: NP_651838.1
• Gene: Chchd3 / 43672
• FlyBaseID: FBgn0010808
• Length: 223
• Species: Drosophila melanogaster
• Alignment Length: 195
• Identity: 49/195 - (25%)
• Similarity: 89/195 - (45%)
• Gaps: 28/195 - (14%)

Human    62 APHKESTLPRSGSSGGQQPSG-----------MKEGVKRYEQEHAAIQDKLFQVAKREREAATK- 114
            |...:|..||:.|.....|:|           :|.|:.:..:||||..::...|.|...:||.|
  Fly     3 ARQSQSREPRTVSMENPTPAGVIDISDDVVKRLKAGISQQAREHAAAAEESKPVPKPTTKAAAKP 67

Human   115 --HSKASLPTGEGSISHEEQKSVRLQ-------ARELESR-EAELRRRDTFYKEQLERIERKNAE 169
              .|.|:.|..:.| |:.....:.:|       |.:::.: ..||.:.|..:||::.::|....:
  Fly    68 AASSPAASPAPKVS-SYPAAVPIYVQGGGHTISAADVQRQMNQELIKNDELWKERMAKLEENLKK 131

Human   170 MYKLSSEQFHEAASKME----STIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCV 230
            ...:..:::..|...:.    ||....:|.| |..|::|:|.|||..|.|.|.|.:.|..:::|:
  Fly   132 TNTILEKEYANAVENVHKRFVSTASSHKVPP-CQDLKSQLLACYRAHPGETLKCIEEVAQFRQCI 195

Human   231  230
              Fly   196  195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHCHD6	NP_001307539.1	MIC19_MIC25	31..189	CDD:461615	33/152 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..90		9/38 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..132		9/28 (32%)
		Cx9C motif 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	198..208		4/9 (44%)
		Cx9C motif 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	219..229		2/9 (22%)
Chchd3	NP_651838.1	DUF1690	<103..193	CDD:429752	23/90 (26%)
		CHCH	163..195	CDD:429096	12/31 (39%)