Protein Alignment POLR3GL and Polr3G

DIOPT Version :10

• Sequence 1: NP_115681.1
• Gene: POLR3GL / 84265
• HGNCID: 28466
• Length: 218
• Species: Homo sapiens
• Sequence 2: NP_788522.1
• Gene: Polr3G / 39941
• FlyBaseID: FBgn0053051
• Length: 211
• Species: Drosophila melanogaster
• Alignment Length: 228
• Identity: 74/228 - (32%)
• Similarity: 108/228 - (47%)
• Gaps: 42/228 - (18%)

Human     7 GRGRG--RGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRG 69
            |||||  .|.||....|: :|....:|..| .|.|.|||:..||..|.:.....|.|..|::...
  Fly     3 GRGRGGKTGTLTAEQMAM-LGCTKDMPVQT-APPPTFPPVLNRPTTLETTATQNYQLLWKEDFLN 65

Human    70 AMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDW------------NPD--WRRLPRELKIR 120
            .||..||::..|  .||.:....|           ||            .||  ::.:|:||.|.
  Fly    66 RMRDSPYYMISA--SRDAKNLDHK-----------DWREKAMERMKLTAQPDFNYKAMPQELNIS 117

Human   121 VRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYD- 184
            .||.:.      ...||...|: |.....:|:.||:||.:....|.:|.::|.:.|:||||:.:
  Fly   118 SRKRRG------ADARPNLLTK-KTNIEDRLKVLEQKELKSGGGEQDENKQESDSEQEEEEDPEA 175

Human   185 --EEEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
              ::|.:|:.||..:||||||.| .|.|||:|:
  Fly   176 ALDDEMDEDNDYGATYFDNGEAF-NDEDDNLDD 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POLR3GL	NP_115681.1	RNA_pol_3_Rpc31	37..204	CDD:463324	55/183 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..218		33/86 (38%)
Polr3G	NP_788522.1	RNA_pol_3_Rpc31	29..196	CDD:463324	55/187 (29%)