DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment HSDL2 and CG13833

DIOPT Version :9

Sequence 1:	NP_115679.2	Gene:	HSDL2 / 84263	HGNCID:	18572	Length:	418	Species:	Homo sapiens
Sequence 2:	NP_651111.1	Gene:	CG13833 / 42718	FlyBaseID:	FBgn0039040	Length:	321	Species:	Drosophila melanogaster

Alignment Length:	197	Identity:	49/197 - (24%)
Similarity:	88/197 - (44%)	Gaps:	18/197 - (9%)

- Green bases have known domain annotations that are detailed below.

Human     8 LAGCTVFITGASRGIGKAIALKAAKDGANIVIA---AKTAQPHPKLLGTIYTAAEEIEAVGGKAL 69
            :||....:|||..|:|:||:|:.||.|.:|.:.   ...|:...|.:..||    ::.|...||
  Fly    50 IAGEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQIQDIY----KVRAKAYKA- 109

Human    70 PCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYLASK 134
                :|.:...:.....|.:::.|.:.:|||||..:...|..:.....:.||:|||....:....
  Fly   110 ----NVTNYDDLVELNSKVVEEMGPVTVLVNNAGVMMHRNMFNPDPADVQLMINVNLTSHFWTKL 170

Human   135 ACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEF----KGEIAVNAL 195
            ..:|.:|:.:...|:.||....:.|:.:.  ..||..|.|...::..:..|.    :.:|.|..:
  Fly   171 VFLPKMKELRKGFIVTISSLAGVFPLPYS--ATYTTTKSGALAHMRTLRMELDLENQKDIHVTTV 233

Human   196 WP 197
            .|
  Fly   234 LP 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HSDL2	NP_115679.2	HSDL2_SDR_c	8..248	CDD:187663	49/197 (25%)
HSDL2	NP_115679.2	SCP2	319..412	CDD:376720
CG13833	NP_651111.1	adh_short	53..241	CDD:278532	47/194 (24%)
CG13833	NP_651111.1	NADB_Rossmann	54..297	CDD:304358	47/193 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1809
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860