DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MPK2 and rl

DIOPT Version :9

Sequence 1:	NP_564746.1	Gene:	MPK2 / 842248	AraportID:	AT1G59580	Length:	376	Species:	Arabidopsis thaliana
Sequence 2:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	174/365 - (47%)
Similarity:	252/365 - (69%)	Gaps:	18/365 - (4%)

- Green bases have known domain annotations that are detailed below.

plant     2 ATPVDPPNG--IRNQGKHYFSMWQTLFEIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIH 64
            :|.|...|.  ||.|          :||:..:|:.:..||.||||:|.|:.:..:|:|||||||
  Fly    16 STEVPQSNAEVIRGQ----------IFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKI- 69

plant    65 NVFENRIDALRTLRELKLLRHLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQV 129
            :.||::....|||||:.:|...:|||::.::|::..:.....:|||:|..||:|||::::| :|.
  Fly    70 SPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLK-TQR 133

plant   130 LSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQ---FMT 191
            |||||..|||:|:|||||||||||:|||||||.|||:|..||||||||||||.::.:..   |:|
  Fly   134 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLT 198

plant   192 EYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREE 256
            |||.||||||||::|....|..|||:||||||.||:|..:|:|||...|:|:..|:.:|||...:
  Fly   199 EYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRD 263

plant   257 DLEFIDNPKAKRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEALQHPYMAP 321
            |||.|.|.||:.|:||||:.|.:.:::|:|.|:.||:|||.|||..:|.|||.|.|||.|||:..
  Fly   264 DLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQ 328

plant   322 LYDPSANPPAQVPIDLDVDEDEDLGAEMIRELMWKEMIHY 361
            .|||...|.|:||..::: |::|:..:.::.|:::|.:.:
  Fly   329 YYDPGDEPVAEVPFRINM-ENDDISRDALKSLIFEETLKF 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MPK2	NP_564746.1	STKc_TEY_MAPK	26..363	CDD:143363	168/339 (50%)
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	168/336 (50%)
rl	NP_001015122.1	S_TKc	38..326	CDD:214567	154/289 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	317	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	349	1.000	Inparanoid score	I618
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	1	1.000	-	-		FOG0000164
OrthoInspector	1	1.000	-	-		otm2432
orthoMCL	1	0.900	-	-		OOG6_100339
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X259
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730