Protein Alignment STX7 and PEP12

DIOPT Version :10

• Sequence 1: NP_003560.2
• Gene: STX7 / 8417
• HGNCID: 11442
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_014679.1
• Gene: PEP12 / 854201
• SGDID: S000005562
• Length: 288
• Species: Saccharomyces cerevisiae
• Alignment Length: 266
• Identity: 65/266 - (24%)
• Similarity: 121/266 - (45%)
• Gaps: 54/266 - (20%)

Human    44 DSP--------------ELRQQLQQKQQYTNQLAKETDK-----------------YIKEFGSL- 76
            |||              |:..|:...||:|..|....|:                 .|:|.|.|
Yeast    22 DSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLI 86

Human    77 ------------PTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVS 129
                        ....|..:.:.|.:::||.:.:.|...||.:|||..:..|:...|.:.|...|
Yeast    87 KKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKESLEAS 151

Human   130 GSFPEDSS---KERNLVSWESQTQP--QVQVQDEEITEDDL----RLIHERESSIRQLEADIMDI 185
             ....|::   :|:...|.:|...|  |:.::.:.|..::.    .||.:|:..|..:|..|.::
Yeast   152 -EMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITEL 215

Human   186 NEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVA 250
            ||:|||||.::.:||.::|:||||:.....:.|.|:.:|.:|..||:::.:....::::|::.:.
Yeast   216 NEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLL 280

Human   251 IISLII 256
            .|.||:
Yeast   281 FIFLIM 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STX7	NP_003560.2	Syntaxin_2	18..119	CDD:464199	25/118 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..148		4/21 (19%)
		SNARE_syntaxin7	168..227	CDD:277228	22/58 (38%)
PEP12	NP_014679.1	COG5325	4..288	CDD:227635	65/266 (24%)